17372-52-0

Basic information

• Product Name: 4,6-DIPHENYL-2-PYRONE
• Synonyms: 4,6-DIPHENYL-2H-PYRAN-2-ONE;4,6-DIPHENYL-2-PYRONE;4,6-DIPHENYLPYR-2(2H)-ONE;3,5-diphenyl-2H-pyran-2-one
• CAS NO: 17372-52-0
• Molecular Formula: C₁₇H₁₂O₂
• Molecular Weight: 248.28
• Mol File: 17372-52-0.mol
• Article Data: 21

Chemical Properties

• Melting Point: 135-138°C
• Boiling Point: 462.2 °C at 760 mmHg
• Flash Point: 195.7 °C
• Appearance: /
• Density: 1.211 g/cm³
• Vapor Pressure: 1.01E-08mmHg at 25°C
• Refractive Index: 1.629
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4,6-DIPHENYL-2-PYRONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIPHENYL-2-PYRONE(17372-52-0)
• EPA Substance Registry System: 4,6-DIPHENYL-2-PYRONE(17372-52-0)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 17372-52-0(Hazardous Substances Data)

Usage

General Description

4,6-DIPHENYL-2-PYRONE is a chemical compound with the molecular formula C18H12O2. It is also known as Benzocoumarin and is a yellow crystalline solid at room temperature. 4,6-DIPHENYL-2-PYRONE is commonly used as a building block in the synthesis of various organic compounds and pharmaceuticals. It has been studied for its potential pharmacological properties, including anti-cancer and anti-microbial activities. Additionally, 4,6-DIPHENYL-2-PYRONE has been investigated for its fluorescent properties and potential use as a fluorescent dye in biological and medical imaging applications. Overall, this compound has a variety of potential applications in the fields of chemistry, pharmacology, and materials science.

InChI:InChI=1/C17H12O2/c18-17-12-15(13-7-3-1-4-8-13)11-16(19-17)14-9-5-2-6-10-14/h1-12H

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 141-97-9 ethyl acetoacetate 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 187407-40-5 (Z)-3,5-diphenylpent-2-en-4-ynoic acid 
• 18777-04-3 (Z)-3-iodo-3-phenyl-2-propenoic acid 
• 101451-40-5 4,6-diphenyl-3,4-dihydro-2H-pyran-2-one 
• 536-74-3 phenylacetylene 
• 637-44-5 phenylpropyolic acid 
• 5411-12-1 chalcone epoxide 
• 124-38-9 carbon dioxide 
• 495-45-4 dypnone 
• 14371-10-9 (E)-3-phenylpropenal 
• 614-21-1 2-nitroacetophenone 
• 16883-69-5 N-phenacylpyridinium bromide 

Downstream Products

• 93321-59-6 4-Benzoyl-3-phenylbut-2-enoic acid 
• 25556-29-0 2,4,6,6-Tetraphenyl-3,6-dihydro-2H-pyran-2-ol 
• 77509-77-4 1,5-dioxo-1-(N-piperidino)-3,5-diphenylpent-2-ene 
• 77509-78-5 1,5-dioxo-1-(N-morpholino)-3,5-diphenylpent-2-ene 
• 81536-49-4 PC₅H₂Ph₃-2.3.5. 
• 81668-35-1 1-ethyl-4,6-diphenyl-2-pyridone 
• 21916-51-8 1-methyl-4,6-diphenylpyridin-2(1H)-one 
• 21916-53-0 1-benzyl-4,6-diphenyl-2-pyridone 
• 76191-98-5 1-<2-chlorobenzyl>-4,6-diphenyl-2-pyridone 
• 72359-31-0 1-(4-methylbenzyl)-4,6-diphenyl-2-pyridone 
• 26478-91-1 4,6-diphenyl-1-hydroxypyridine-2-one 
• 29261-44-7 2-(6-hydroxy-4-phenylpyridin-2-yl)phenyl 
• 345208-94-8 3-bromo-4,6-diphenyl-pyran-2-one 
• 32503-76-7 2-tert-Butyl-4,6-diphenylphosphinine 

Relevant articles and documents

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Synthetic Access to gem-Difluoropropargyl Vinyl Ethers and Their Application to Propargyl Claisen Rearrangement

With the increasing importance of fluorine to medicinal chemistry and other areas, methods to access various fluorinated compounds are needed. Herein, we report the synthesis of difluoropropargyl vinyl ethers from ketones and aldehydes using difluoropropargyl bromide dicobalt complexes. We applied difluoropropargyl vinyl ethers to the synthesis of difluorodienone or difluoroallene under thermal conditions and trifluoro-pyran under acid-catalyzed conditions.

Regioselective Synthesis of 5-Metalated 2-Pyrones by Intramolecular Oxymetalation of Carbonyl-ene-yne Compounds Using Indium Trihalide

The oxyindation of carbonyl-ene-yne compounds with indium trihalides proceeded efficiently to give di-, tri-, and tetrasubstituted 2-pyrones bearing a carbon-indium bond. The metalated 2-pyrone and a zwitterion intermediate were identified by X-ray crystallographic analysis. The application of organoindium compounds to oxidation or cross-coupling provided easy access to various multifunctionalized 2-pyrones. Some 2-pyrone derivatives show intense fluorescence only in the solid state (aggregation-induced emission).