174626-26-7Relevant articles and documents
DEUTERATED FORMS OF AMINOSTEROLS AND METHODS OF USING THE SAME
-
Paragraph 0473; 0474, (2020/08/30)
Described are deuterated forms of aminosterols, or a pharmaceutically acceptable salt thereof, wherein one or more hydrogen atoms at one or more positions selected from C1, C2, C3, C4, C5, C6, C7, C8, C9, C11, C12, C14, C15, C16, C17, C18, C19, C20, C21,
Study on the Structure Activity Relationships of NPTX-594, a Spider Toxin Belonging to the Type-B Acylpolyamine Structure
Wakamiya, Tateaki,Kinoshita, Tomohiko,Hattori, Yoshihide,Yamaguchi, Yoshihiro,Naoki, Hideo,Corzo, Gerardo,Nakajimal, Terumi
, p. 331 - 340 (2007/10/03)
In order to elucidate the structure activity relationships of the spider toxin termed NPTX-594, eleven toxin analogs were designed and synthesized, and their paralytic activities against cricket were tested. As a result of the present study, it was clarif
Condensed-purines syntheses of tetrahydro-1,4-diazepino[1,2,3-gh]purin- 2-one and hexahydro-1,4-diazocino[1,2,3-gh]purin-2-one
Suzuki, Hirokazu,Sawanishi, Hiroyuki,Yamamoto, Kenji,Miyamoto, Ken-Ichi
, p. 1322 - 1325 (2007/10/03)
1,4-Pyrimido- (2a), 1,4-diazepino- (2b), and 1,4-diazocino[1,2,3- gh]purine (2c) were designed as selective cAMP-phosphodiesterase 4 (PDE 4) inhibitors. The desired condensed-purines (2b,c) were synthesized by reaction of 7-aminoalkyl-3-propylpurine-2,4-d