17650-84-9 Usage
Description
Nicotiflorin is a flavonoid that has been found in I. glandulifera and has antioxidant and neuroprotective activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS radicals with EC50 values of 0.52 and 0.48 mg/ml, respectively, in cell-free assays. Nicotiflorin (1 μM) prevents hydrogen peroxide-induced decreases in tyrosine hydroxylase activity in PC12 cells and cell death in primary rat mesencephalic neurons. It decreases infarct volume by 24.5, 45.8, and 63.2% when administered at doses of 2.5, 5, and 10 mg/kg, respectively, in a rat model of cerebral ischemia-reperfusion injury induced by transient middle central artery occlusion (MCAO).
Uses
Kaempferol 3-O-β -Rutinoside is a flavonoid antioxidant compound from Cichorium spinosum L. ecotype plants and also may display anti-diabetic activity. It is a component of many plant species including Helianthemum ruficomum.
General Description
Kaempferol 3-O-β -rutinoside is a bitter tasting flavonol glycoside that was isolated from flowers of a Clematis cultivar.
Check Digit Verification of cas no
The CAS Registry Mumber 17650-84-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,6,5 and 0 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 17650-84:
(7*1)+(6*7)+(5*6)+(4*5)+(3*0)+(2*8)+(1*4)=119
119 % 10 = 9
So 17650-84-9 is a valid CAS Registry Number.
InChI:InChI=1/C27H30O15/c1-9-17(31)20(34)22(36)26(39-9)38-8-15-18(32)21(35)23(37)27(41-15)42-25-19(33)16-13(30)6-12(29)7-14(16)40-24(25)10-2-4-11(28)5-3-10/h2-7,9,15,17-18,20-23,26-32,34-37H,8H2,1H3/t9-,15+,17-,18+,20+,21-,22+,23+,26+,27-/m0/s1
17650-84-9Relevant articles and documents
Kaempferol and its glycosides from Equisetum silvaticum L. from the khanty-mansi autonomous area
Bonacheva,Botirov, E. Kh.
, p. 777 - 780 (2015/01/30)
Three flavonoids were isolated from the aerial part of the wood horsetail (Equisetum silvaticum L.); two of them were found for the first time. The compounds were identified as kaempferol, kaempferol 3-O-β-D-galactopyranosyl-7-O-α-L-rhamnopyranoside and kaempferol 3-O-rutinosyl-7-O-L-rhamnopyranoside on the basis of the chemical transformations and IR, UV, 1H-NMR and mass spectra.
Two flavonol glycosides from seeds of Camellia sinensis.
Sekine,Arita,Yamaguchi,Saito,Okonogi,Morisaki,Iwasaki,Murakoshi
, p. 991 - 995 (2007/10/02)
Two novel flavonol triglycosides, camelliaside A and B, have been isolated from seeds of Camellia sinensis. The structures were determined to be kaempferol 3-O-[2-O-beta-D- galactopyranosyl-6-O-alpha-L-rhamnopyranosyl]-beta-D-glucopyranoside and kaempferol 3-O-[2-O-beta- D-xylopyranosyl-6-O-alpha-L-rhamnopyranosyl]-beta-D-glucopyranoside on the basis of spectroscopic, chemical and enzymatic studies. These types of interglycosidic linkages, Gal(1----2)[Rha(1----6)]Glc and Xyl(1----2)[Rha(1----6)]Glc, have not been reported previously in flavone and flavonol glycosides.
Constituents of Cupuliferae, II. - A New Acylated Flavonoid Glycoside from Castanea sativa Mill.
Romussi, Giovanni,Mosti, Luisa,Bignardi, Gaetano
, p. 761 - 764 (2007/10/02)
From leaves of Castanea sativa Mill. in addition to tiliroside , 3>, a new acylated flavonoid glycoside has been isolated and identified as kaempferol 3-O-Glc-(p-coumaroyl)-α-L-rhamnopyranosyl-(1->6)-β-D-glucopyranoside> (1).
