177980-09-5

Basic information

• Product Name: 3'-O-acetyl-2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine
• CAS NO: 177980-09-5
• Molecular Weight: 613.627
• Mol File: 177980-09-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3'-O-acetyl-2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-O-acetyl-2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine(177980-09-5)
• EPA Substance Registry System: 3'-O-acetyl-2'-azido-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)uridine(177980-09-5)

Safety Data

• Hazardous Substances Data: 177980-09-5(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 177980-10-8 2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine 
• 173170-12-2 2,2'-O-anhydro-1-<5'-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl>uracil 

Downstream Products

• 213487-23-1 2'-azido-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine 
• 213487-27-5 (1-{(2R,3R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-tetrahydro-furan-2-yl}-2-oxo-1,2-dihydro-pyrimidin-4-yl)-carbamic acid 2-(4-nitro-phenyl)-ethyl ester 
• 213487-25-3 Carbonic acid (2R,3S,4R,5R)-4-azido-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{4-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-3-yl ester 2-(4-nitro-phenyl)-ethyl ester 

Relevant articles and documents

Synthesis of oligonucleotides containing 2'-azido-and 2'-amino-2'-deoxyuridine using phosphotriester chemistry

The phosphotriester method of oligonucleotide synthesis is shown to be useful for assembly of oligomers containing multiple internal 2'-azido substituents. Subsequent reduction of the azido group(s) with trialkylphosphines provides 2'-amino substituted oligonucleotides.