17922-79-1

Basic information

• Product Name: N-Cyclohexyl L-Z-ValinaMide
• Synonyms: N-Cyclohexyl L-Z-ValinaMide;(S)-Benzyl (1-(cyclohexylamino)-3-methyl-1-oxobutan-2-yl)carbamate
• CAS NO: 17922-79-1
• Molecular Formula: C₁₉H₂₈N₂O₃
• Molecular Weight: 332.43722
• Mol File: 17922-79-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-Cyclohexyl L-Z-ValinaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Cyclohexyl L-Z-ValinaMide(17922-79-1)
• EPA Substance Registry System: N-Cyclohexyl L-Z-ValinaMide(17922-79-1)

Safety Data

• Hazardous Substances Data: 17922-79-1(Hazardous Substances Data)

Usage

General Description

N-Cyclohexyl L-Z-ValinaMide is a chemical compound that consists of a cyclohexyl group attached to a valinamide molecule. It is commonly used in research and pharmaceutical development as a building block in the synthesis of various compounds. The cyclohexyl group provides stability and can influence the compound's solubility and pharmacokinetic properties. The valinamide molecule, which is a derivative of the amino acid valine, can contribute to the compound's biological activity and potential therapeutic effects. Overall, N-Cyclohexyl L-Z-ValinaMide is a versatile and important chemical in the field of medicinal chemistry and drug discovery.

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 108-91-8 cyclohexylamine 
• 10512-93-3 Z-Val-ONp 
• 72-18-4 L-valine 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 132949-30-5 N-((2-hydroxy-1-naphthyl)methylene)-(S)-valine cyclohexylamide 
• 143592-34-1 Ps-S-Val-NHCy 
• 46339-96-2 L-N-cyclohexylvalinamide 

Relevant articles and documents

Synthesis, characterization and docking studies of anti-HCV molecules

The present study reports the synthesis and characterization of novel molecules inhibiting the spread of hepatitis C. The molecules were designed as to block the NS3/4A protease enzyme on HCV RNA. The molecules were synthesized using usual peptide synthesis techniques. Compounds with purity more than 95% were characterized and docking studies were also performed. All the compounds were characterized using physico-chemical techniques such as determination of melting point by DSC and NMR, mass, IR spectral studies. The docking studies were also conducted to assess the activity of molecules for inhibition of hepatitis C virus.

A catalyst for asymmetric induction

A catalyst for asymmetric induction is provided which comprises a titanium (IV) alkoxide and an amino acid amide derivative of formula (I): wherein R1 is isopropyl, isobutyl, sec-butyl, tert-butyl, phenyl or benzyl, R2 and R3 are the same or different and each is lower alkyl, C3 to C8 cycloalkyl, unsubstituted or substituted phenyl or hydrogen or R2 and R3 together form a divalent C3 to C7 alkylene group optionally containing one or more hetero atoms, R4 is chlorine, bromine, iodine, lower alkyl or unsubstituted or substituted phenyl, R5, R6 and R7 are the same or different and each is hydrogen, halogen, methyl or methoxy or R5 is as defined above and R6 and R7 together form -CH=CH-CH=CH- or -OCH2O- or R7 is as defined above and R5 and R6 together form -CH=CH-CH=CH- or -OCH2O- and * denotes an absolute configuration of S or R.