179526-94-4 Usage
Description
(4'-fluoro-[1,1'-biphenyl]-2-yl)boronic acid, also known as 4'-fluoro-2-biphenylboronic acid, is a boronic acid derivative characterized by the chemical formula C12H10BFO2. It is a significant compound in the field of organic chemistry, particularly for its role in the synthesis of various pharmaceutical intermediates and active ingredients, as well as its potential applications in materials science.
Uses
Used in Organic Synthesis:
(4'-fluoro-[1,1'-biphenyl]-2-yl)boronic acid is utilized as a reagent in the Suzuki-Miyaura cross-coupling reaction, a widely recognized method for forming carbon-carbon bonds. This reaction is essential for creating complex organic molecules, which are vital in the development of new pharmaceuticals and advanced materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (4'-fluoro-[1,1'-biphenyl]-2-yl)boronic acid serves as a key component in the synthesis of pharmaceutical intermediates and active ingredients. Its unique structure allows for the creation of a variety of biologically active compounds, contributing to the advancement of drug discovery and development.
Used in Materials Science:
(4'-fluoro-[1,1'-biphenyl]-2-yl)boronic acid also has potential applications in materials science, particularly in the development of organic electronic materials and polymer chemistry. Its incorporation into these materials can lead to improved properties and performance, making it a valuable asset in the creation of innovative materials for various applications.
Overall, (4'-fluoro-[1,1'-biphenyl]-2-yl)boronic acid is a versatile and essential compound in the fields of organic chemistry, pharmaceuticals, and materials science, playing a crucial role in the synthesis of important compounds and the development of new technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 179526-94-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,5,2 and 6 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 179526-94:
(8*1)+(7*7)+(6*9)+(5*5)+(4*2)+(3*6)+(2*9)+(1*4)=184
184 % 10 = 4
So 179526-94-4 is a valid CAS Registry Number.
179526-94-4Relevant articles and documents
Ag-Catalyzed Cyclization of Arylboronic Acids with Elemental Selenium for the Synthesis of Selenaheterocycles
Gao, Wen-Xia,Huang, Xiao-Bo,Liu, Miao-Chang,Wu, Hua-Yue,Zhang, Xue,Zhou, Yun-Bing
, p. 5639 - 5644 (2020/11/30)
A general method for the synthesis of five-membered and six-membered selenaheterocycles through Ag-catalyzed C?Se bond-forming reaction is reported. This reaction proceeds via intramolecular cyclization of arylboronic acids with selenium powder. Preliminary mechanism studies demonstrate that this transformation involves a selenium-centred radical intermediate. (Figure presented.).
COMBINATIONS COMPRISING AN Hsp90 INHIBITOR AND A PHOPHODIESTERASE INHIBITOR FOR TREATING OR PREVENTING NEOPLASIA
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Page/Page column 165, (2008/06/13)
A method for treating or preventing neoplasia or a neoplasia-related disorder in a subject is provided, the method comprising administering to the subject an effective amount of a combination comprising an Hsp90 inhibitor and a phosphodiesterase inhibitor, and optionally a Cox-2 inhibitor.
Substituted terphenyl compounds for the treatment of inflammation
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, (2008/06/13)
A class of terphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: STR1 wherein each of R2 and R3 is independently selected from hydrido and halo; or wherein R2 and R3 together form --OCH2 O--; wherein each of R6 through R8 is independently selected from hydrido, lower alkyl, halo, lower alkoxy, lower haloalkyl, and lower dialkylamino; or wherein R6 and R7 together form --OCH2 O; and wherein R12 is selected from lower alkylsulfonyl and aminosulfonyl; or a pharmaceutically-acceptable salt thereof.
