183864-20-2

Basic information

• Product Name: 2-Propen-1-amine, N-[(2-bromophenyl)methylene]-, (E)-
• CAS NO: 183864-20-2
• Molecular Formula: C10H10BrN
• Molecular Weight: 224.1
• Mol File: 183864-20-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-amine, N-[(2-bromophenyl)methylene]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-amine, N-[(2-bromophenyl)methylene]-, (E)-(183864-20-2)
• EPA Substance Registry System: 2-Propen-1-amine, N-[(2-bromophenyl)methylene]-, (E)-(183864-20-2)

Safety Data

• Hazardous Substances Data: 183864-20-2(Hazardous Substances Data)

Upstream product

• 107-11-9 1-amino-2-propene 
• 6630-33-7 ortho-bromobenzaldehyde 
• 106-95-6 allyl bromide 

Downstream Products

• 243455-68-7 1-allyl-4-(2-bromo-phenyl)-3-phenoxy-azetidin-2-one 
• 130517-97-4 benzyl-cyclohexylmethylene-amine 
• 1272012-49-3 N-allyl-N-(1-(2-bromophenyl)but-3-enyl)-2,2,2-trifluoroacetamide 
• 1272012-51-7 1-[2-(2-bromo-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-2,2,2-trifluoro-ethanone 
• 1619829-57-0 N-allyl-N-(1-(2-bromophenyl)-3-(4-(dimethylamino)phenyl)prop-2-yn-1-yl)benzamide 
• 1428883-56-0 N-allyl-N-(1-(2-bromophenyl)-3-phenylprop-2-yn-1-yl)-benzamide 
• 1619829-61-6 N-allyl-N-(1-(2-bromophenyl)-3-(naphthalen-1-yl)prop-2-yn-1-yl)benzamide 
• 1428883-74-2 N-allyl-N-(1-(2-bromophenyl)-3-(4-methoxyphenyl)prop-2-yn-1-yl)benzamide 

Relevant articles and documents

Iron-Catalyzed Reductive Ethylation of Imines with Ethanol

The borrowing hydrogen strategy has been applied to the ethylation of imines with an air-stable iron complex as precatalyst. This approach opens new perspectives in this area as it enables the synthesis of unsymmetric tertiary amines from readily available substrates and ethanol as a C2 building block. A variety of imines bearing electron-rich aryl or alkyl groups at the nitrogen atom could be efficiently reductively alkylated without the need for molecular hydrogen. The mechanism of this reaction, which shows complete selectivity for ethanol over other alcohols, has been studied experimentally and by means of DFT computations.

An effective method to prepare imines from aldehyde, bromide/epoxide, and aqueous ammonia

A three-component reaction of aldehydes, alkyl bromides, and ammonia to form imines was studied. Aqueous ammonia was applied as the nitrogen source and solvent in the reaction. For the aromatic aldehyde, the product yields are good to excellent and the reaction conditions are mild to be compatible with a range of functional groups. The reaction of aldehydes and aqueous ammonia with epoxides was also studied and imines bearing a vicinal hydroxyl group can be obtained efficiently and regioselectively. And studies showed that this method allows the synthesis of primary amines and especially 1,2-amino alcohol selectively in high yield. It is proposed that the reaction pathway might involve a key intermediate of hydrobenzamide.

A novel entry toward 2-imino-1,3-thiazolidines and 2-imino-1,3-thiazolines by ring transformation of 2-(thiocyanomethyl)aziridines

(Chemical Equation Presented). A new, efficient, and straightforward synthesis of 3-arylmethyl-4-chloromethyl-2-imino-1,3-thiazolidines and 2-(N-acylimino)-3-arylmethyl-4-chloromethyl-1,3-thiazolidines has been developed by ring transformation of 1-arylme