18440-53-4

Basic information

• Product Name: Hydrazine, 1,2-bis(4-methylphenyl)-1,2-diphenyl-
• CAS NO: 18440-53-4
• Molecular Formula: C26H24N2
• Molecular Weight: 364.49
• Mol File: 18440-53-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Hydrazine, 1,2-bis(4-methylphenyl)-1,2-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazine, 1,2-bis(4-methylphenyl)-1,2-diphenyl-(18440-53-4)
• EPA Substance Registry System: Hydrazine, 1,2-bis(4-methylphenyl)-1,2-diphenyl-(18440-53-4)

Safety Data

• Hazardous Substances Data: 18440-53-4(Hazardous Substances Data)

Upstream product

• 620-84-8 4-methyldiphenylamine 
• 99-99-0 1-methyl-4-nitrobenzene 
• 5720-05-8 4-methylphenylboronic acid 
• 62-53-3 aniline 

Downstream Products

• 620-84-8 4-methyldiphenylamine 
• 129533-52-4 5,10-di(4-tolyl)-5,10-dihydrophenazine 

Relevant articles and documents

Electrochemical Reductive Arylation of Nitroarenes with Arylboronic Acids

The synthesis of diarylamine is extremely important in organic chemistry. Herein, a novel electrochemical reductive arylation of nitroarenes with arylboronic acids was developed. A variety of diarylamines were synthesized without the need for transition-metal catalysts. The reaction could be scaled up efficiently in a flow cell and several derivatization reactions were carried out smoothly. Cyclic voltammetry experiments and mechanism studies showed that acetonitrile, formic acid, and triethyl phosphite all played a role in promoting this reductive arylation transformation.

Tunable Electrochemical C?N versus N?N Bond Formation of Nitrogen-Centered Radicals Enabled by Dehydrogenative Dearomatization: Biological Applications

Herein, an environmentally friendly electrochemical approach is reported that takes advantage of the captodative effect and delocalization effect to generate nitrogen-centered radicals (NCRs). By changing the reaction parameters of the electrode material and feedstock solubility, dearomatization enabled a selective dehydrogenative C?N versus N?N bond formation reaction. Hence, pyrido[1,2-a]benzimidazole and tetraarylhydrazine frameworks were prepared through a sustainable transition-metal- and exogenous oxidant-free strategy with broad generality. Bioactivity assays demonstrated that pyrido[1,2-a]benzimidazoles displayed antimicrobial activity and cytotoxicity against human cancer cells. Compound 21 exhibited good photochemical properties with a large Stokes shift (approximately 130 nm) and was successfully applied to subcellular imaging. A preliminary mechanism investigation and density functional theory (DFT) calculations revealed the possible reaction pathway.

Facile Cu(I)-catalyzed oxidative coupling of anilines to azo compounds and hydrazines with diaziridinone under mild conditions

A mild and highly efficient Cu(I)-catalyzed oxidative coupling of anilines is described. Various primary and secondary anilines can be efficiently coupled under mild conditions to the corresponding azo compounds and hydrazines in high yields. This method provides a direct and practical access to these compounds and is also amenable to gram scale with no special precautions to exclude air or moisture.