185122-63-8

Basic information

• Product Name: 5-BROMO-1-INDANONE OXIME
• Synonyms: 5-BROMO-1-INDANONE OXIME
• CAS NO: 185122-63-8
• Molecular Formula: C₉H₈BrNO
• Molecular Weight: 226.06992
• Mol File: 185122-63-8.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 346.5±41.0 °C(Predicted)
• Appearance: /
• Density: 1.67±0.1 g/cm3(Predicted)
• PKA: 11.12±0.20(Predicted)
• CAS DataBase Reference: 5-BROMO-1-INDANONE OXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-1-INDANONE OXIME(185122-63-8)
• EPA Substance Registry System: 5-BROMO-1-INDANONE OXIME(185122-63-8)

Safety Data

• Hazardous Substances Data: 185122-63-8(Hazardous Substances Data)

Usage

Description

5-Bromo-1-indanone oxime is a chemical compound characterized by the molecular formula C9H8BrNO and a molar mass of 222.07 g/mol. It is a white to yellow crystalline solid that is predominantly utilized in organic synthesis and research. 5-BROMO-1-INDANONE OXIME's oxime functionality renders it a versatile building block for the synthesis of a variety of organic compounds, particularly pharmaceuticals. The presence of bromo and indanone moieties in its structure endows it with unique reactivity and applications, making it a valuable asset in the realm of organic chemistry.

Uses

Used in Organic Synthesis:
5-Bromo-1-indanone oxime is employed as a key intermediate in the synthesis of various organic compounds. Its unique structure and reactivity make it a preferred choice for the development of new chemical entities.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Bromo-1-indanone oxime is used as a building block for the synthesis of biologically active compounds. Its oxime functionality and other structural features contribute to the creation of potential drug candidates.
Used in Research:
5-Bromo-1-indanone oxime is utilized as a reagent in academic and industrial research settings. It aids in the preparation of complex organic molecules and the study of organic reaction mechanisms, furthering the understanding of chemical processes and the development of novel synthetic routes.
Used in the Study of Organic Reaction Mechanisms:
5-Bromo-1-indanone oxime is applied in the investigation of reaction mechanisms in organic chemistry. Its participation in various chemical reactions provides insights into the underlying processes and helps in optimizing reaction conditions for better yields and selectivity.

Upstream product

• 34598-49-7 5-Bromo-1-indanone 
• 31736-73-9 4-bromophenyl 2-chloroethyl ketone 
• 108-86-1 bromobenzene 

Downstream Products

• 1187196-68-4 tert-butyl N-[5-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)-2.4-dihydropyrrol-5-yl]indan-1-yl]carbamate 
• 1187512-62-4 N-[5-[3-(3,5-dichlorophenyl)-3-(trifluoromethyl)-2,4-dihydropyrrol-5-yl]indan-1-yl]acetamide 
• 1555862-60-6 5-[3-[3,5-bis(trifluoromethyl)phenyl]-3-(trifluoromethyl)pyrrolidin-1-yl]indan-1-amine 
• 1199829-02-1 ethyl 1-((1-(benzyloxycarbonylamino)-2,3-dihydro-1H-inden-5-yl)methyl)-3-(trifluoromethyl)-1H-pyrazole-4-carboxylate 
• 1199828-95-9 N-(5-((4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,3-dihydro-1H-inden-1-yl)-2-methoxybenzenesulfonamide 
• 1199829-04-3 benzyl 5-((4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,3-dihydro-1H-inden-1-ylcarbamate 
• 1199828-99-3 methyl 1-(benzyloxycarbonylamino)-2,3-dihydro-1H-indene-5-carboxylate 
• 1251457-86-9 benzyl 5-(chloromethyl)-2,3-dihydro-1H-inden-1-ylcarbamate 
• 1199829-00-9 benzyl 5-(hydroxymethyl)-2,3-dihydro-1H-inden-1-ylcarbamate 
• 1199828-97-1 benzyl 5-bromo-2,3-dihydro-1H-inden-1-ylcarbamate 
• 1455457-34-7 N-(5-{3-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl}-2,3-dihydro-1H-inden-1-yl)propanamide 
• 1221771-61-4 N-(5-{3-[3,5-bis(trifluoromethyl)phenyl]-3-(trifluoromethyl)pyrrolidin-1-yl}-2,3-dihydro-1H-inden-1-yl)propanamide 
• 185122-74-1 5-bromo-2,3-dihydro-1H-inden-1-one oxime 
• 1338926-70-7 N-{5-[4,4,4-trifluoro-3-(nitromethyl)-3-(3,4,5-trichloro-phenyl)butanoyl]-2,3-dihydro-1H-inden-1-yl}propanamide 

Relevant articles and documents

Deconstructive Oxygenation of Unstrained Cycloalkanamines

A deconstructive oxygenation of unstrained primary cycloalkanamines has been developed for the first time using an auto-oxidative aromatization promoted C(sp3)?C(sp3) bond cleavage strategy. This metal-free method involves the substitution reaction of cycloalkanamines with hydrazonyl chlorides and subsequent auto-oxidative annulation to in situ generate pre-aromatics, followed by N-radical-promoted ring-opening and further oxygenation by 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) and m-cholorperoxybenzoic acid (mCPBA). Consequently, a series of 1,2,4-triazole-containing acyclic carbonyl compounds were efficiently produced. This protocol features a one-pot operation, mild reaction conditions, high regioselectivity and ring-opening efficiency, broad substrate scope, and is compatible with alkaloids, osamines, and peptides, as well as steroids.

ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

A compound of formula (I): wherein the substituents are as defined in the description. Medicinal products containing the same which are useful in treating or preventing pathologies which are the result of activation of the RhoA/ROCK pathway and phosphorylation of the myosin light chain.

METHODS OF PEST CONTROL IN SOYBEAN

The invention provides methods comprising applying to a crop of soybean plants, the locus thereof, or propagation material thereof, a compound of formula (I) wherein -B1-B2-B3- is -C=N-O-, -C=N-CH2- or -N-CH2-CH2-; Y1, Y2 and Y3 are independently CH or nitrogen; wherein no more than two of Y1, Y2 and Y3 are nitrogen and wherein Y2 and Y3 are not both nitrogen; R9 is C1-C4alkyl, C1-C4haloalkyl, C1-C4alkyl-O-CH2-, C1-C4haloalkyl-O-CH2-,C3-C6cycloalkyl, C3-C6cycloalkyl-CH2-, C1-C4alkyl-S-CH2-, C1-C4alkyl-S(O)-CH2-, or C1-C4alkyl-S(O2)-CH2-; X2 is C-X6 or nitrogen; X1, X3 and X6 are independently hydrogen, halogen or trihalomethyl, wherein at least two of X1, X3 and X6 are not hydrogen; X4 is trifluoromethyl, difluoromethyl or chlorodifluoromethyl. Preferably the methods are for control of stinkbugs, in particular from the genus Euschistus and in particular the species Euschistus heros.