1859-00-3

Basic information

• Product Name: Benzenecarboximidamide, N-(4-methylphenyl)-
• Synonyms: N'-m-tolyl-benzamidine
• CAS NO: 1859-00-3
• Molecular Formula: C14H14N2
• Molecular Weight: 210.279
• Mol File: 1859-00-3.mol
• Article Data: 47

Chemical Properties

• CAS DataBase Reference: Benzenecarboximidamide, N-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenecarboximidamide, N-(4-methylphenyl)-(1859-00-3)
• EPA Substance Registry System: Benzenecarboximidamide, N-(4-methylphenyl)-(1859-00-3)

Safety Data

• Hazardous Substances Data: 1859-00-3(Hazardous Substances Data)

Upstream product

• 59410-82-1 (S)-α-phenylglycine ethyl ester hydrochloride 
• 106-49-0 p-toluidine 
• 100-47-0 benzonitrile 
• 1613-92-9 (E)-N-benzylidene-4-toluidine 
• 540-23-8 p-toluidine hydrochloride 
• 42259-31-4 1,1-bis(piperidinyl)ethylene 
• 66275-61-4 N-Chloro-N'-(4-methylphenyl)benzamidine 
• 99-99-0 1-methyl-4-nitrobenzene 
• 60-29-7 diethyl ether 
• 108-88-3 toluene 
• 618-39-3 benzamidin 
• 5720-05-8 4-methylphenylboronic acid 
• 55-21-0 benzamide 
• 29540-83-8 p-tolyl triflate 

Downstream Products

• 69709-71-3 1-ethyl-7-methyl-3-phenyl-1λ⁴,2,4-benzothiadiazine 
• 69709-69-9 1,7-dimethyl-3-phenyl-1λ⁴,2,4-benzothiadiazine 
• 2963-65-7 5-methyl-2-phenyl-1H-1,3-benzimidazole 
• 94078-46-3 1-(4-Chloro-phenyl)-3-[1-phenyl-1-p-tolylamino-meth-(Z)-ylidene]-thiourea 
• 16107-83-8 6-methyl-2,4-diphenyl-quinazoline 
• 136801-40-6 6-methyl-4-(4'-methoxyphenyl)-2-phenylquinazoline 
• 1242182-90-6 6-methyl-2-phenyl-4-[(triisopropylsilyl)methyl]quinazoline 
• 1325218-03-8 N-cyclohexyl-4-amino-6-methyl-2-phenylquinazoline 
• 1325217-81-9 N-tert-butyl-4-amino-6-methyl-2-phenylquinazoline 
• 1325218-02-7 N-isopropyl-4-amino-6-methyl-2-phenylquinazoline 
• 1325218-07-2 N-(3,5-dimethylphenyl)-4-amino-6-methyl-2-phenylquinazoline 
• 1325218-04-9 N-(2,6-dimethylphenyl)-4-amino-6-methyl-2-phenylquinazoline 
• 1325218-06-1 N-(2,4-dimethylphenyl)-4-amino-6-methyl-2-phenylquinazoline 
• 1325218-05-0 N-(2-tert-butylphenyl)-4-amino-6-methyl-2-phenylquinazoline 

Relevant articles and documents

Photoredox synthesis of functionalized quinazolinesviacopper-catalyzed aerobic oxidative Csp2-H annulation of amidines with terminal alkynes

We have developed a visible light-induced photo-redox copper-catalyzed oxidative Csp2-H annulation (Friedel-Crafts-type cyclization) of amidines with terminal alkynes at room temperature to synthesize functionalized quinazolines. We report copp

Synthesis of aminoisoquinolines via Rh-catalyzed [4 + 2] annulation of benzamidamides with vinylene carbonate

A new strategy is developed for the synthesis of 1-aminoisoquinoline derivatives. This Rh(III)-catalyzed [4 + 2] annulation reaction employs benzamidines as efficient directing groups and the vinylene carbonate as an acetylene surrogate. Additionally, the reaction features broad substrate scopes and good yields, only producing carbonate anion as byproduct.

Practical Synthesis of Benzimidazo[1,2- A[quinolines via Rh(III)-Catalyzed C-H Activation Cascade Reaction from Imidamides and Anthranils

We report a novel and practical one-pot Rh(III)-catalyzed strategy to construct benzimidazo[1,2-a]quinolines from readily available imidamides and anthranils. The cascade reaction proceeds via a C-H amination-cyclization-cyclization process in ionic liquid without any additives and possesses simple operation, moderate-to-high yield, and broad substrate scope features, which will provide the reference for the construction of biologically active fused benzimidazoles.