1883595-37-6 Usage
Description
5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid is an organic compound with a complex chemical structure, characterized by the presence of a pyrrole ring, a fluorophenyl group, and a pyridinyl sulfonyl group. It is a derivative of pyrrole-3-carboxylic acid, which is a heterocyclic compound with potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid is used as an impurity in the synthesis of Vonoprazan, a novel potassium-competitive acid blocker. Vonoprazan is utilized for the treatment of acid-related diseases, such as gastroesophageal reflux disease (GERD) and peptic ulcers. The presence of this compound as an impurity in Vonoprazan may affect the drug's efficacy and safety, making it essential to monitor and control its levels during the manufacturing process.
Used in Chemical Research:
5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxylic acid can also be used as a starting material or intermediate in the synthesis of various other organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, or materials science industries. Its unique structure and functional groups make it a valuable building block for the development of new molecules with specific properties and activities.
Check Digit Verification of cas no
The CAS Registry Mumber 1883595-37-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,8,3,5,9 and 5 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1883595-37:
(9*1)+(8*8)+(7*8)+(6*3)+(5*5)+(4*9)+(3*5)+(2*3)+(1*7)=236
236 % 10 = 6
So 1883595-37-6 is a valid CAS Registry Number.
1883595-37-6Relevant articles and documents
Identification, characterization, synthesis of major metabolites biotransformed from vonoprazan fumarate
Hu, Ji'an,Kou, Jingping,Li, Jianbing,Li, Yanhua,Lin, Biyue,Wang, Zhongqing,Wu, Shuming,Xiao, Qingbo,Xin, Libo,Zhou, Xinglin,Zhu, Zhu
, (2022/02/10)
A first synthetic research concerning four observed metabolites and their deuterium-labeled analogues of reflux esophagitis drug vonoprazan fumarate is reported. Among which the synthetic methods of three metabolites M ? I, M-III, M-IV-Sul, and four stable isotop labeled analogues M-I-d4, M-II-d4, M-III-d4, M-IV-Sul-d4 have not yet been reported before. The structures of these compounds were elucidated on the basis of MS and NMR spectroscopy.
