312307-38-3 Usage
Description
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile, also known as Vonoprazan Impurity 32, is an organic compound derived from Vonoprazan, a potassium-competitive acid blocker (P-CAB). It is characterized by its unique molecular structure, which includes a fluorophenyl group and a propanedinitrile moiety. 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile is typically found as an impurity in the synthesis or production process of Vonoprazan.
Uses
Used in Pharmaceutical Industry:
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile is used as an impurity in the production of Vonoprazan, a P-CAB medication, for the treatment of gastric acid-related disorders. The presence of this impurity is crucial for quality control and safety assessments, as it can impact the efficacy and safety profile of the final drug product.
Used in Quality Control and Safety Assessments:
In the pharmaceutical industry, 2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile serves as a reference compound for quality control and safety assessments of Vonoprazan. By monitoring the levels of this impurity, manufacturers can ensure that the final drug product meets the required standards for purity, efficacy, and safety.
Used in Research and Development:
2-[2-(2-Fluorophenyl)-2-oxoethyl]propanedinitrile may also be used in research and development for the study of P-CABs and their potential applications in treating gastric acid-related disorders. Understanding the properties and effects of this impurity can contribute to the development of new drugs or improvements in the synthesis and production processes of existing medications.
Check Digit Verification of cas no
The CAS Registry Mumber 312307-38-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,2,3,0 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 312307-38:
(8*3)+(7*1)+(6*2)+(5*3)+(4*0)+(3*7)+(2*3)+(1*8)=93
93 % 10 = 3
So 312307-38-3 is a valid CAS Registry Number.
312307-38-3Relevant articles and documents
Synthesis method of 5-(2-fluorophenyl)-1H-pyrrole-3-formaldehyde
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, (2021/01/20)
The invention discloses a synthetic method of 5-(2-fluorophenyl)-1H-pyrrole-3-formaldehyde, and belongs to the field of organic synthesis. The preparation method comprises the following steps: (1) reacting 2-fluoro acetophenone with a bromination reagent
A fumaric acid fertile norah approves key intermediate and its preparation method (by machine translation)
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Paragraph 0170; 0181; 0188-0194, (2017/10/07)
The present invention provides a kind of fumaric acid fertile norah approves key intermediate and its preparation method. The invention fumaric acid fertile norah approves a key intermediate in the preparation method mainly comprises 3 step process, the p
