18940-57-3

Basic information

• Product Name: Piperazine, 1,4-diacetyl- (6CI,8CI,9CI)
• Synonyms: Piperazine, 1,4-diacetyl- (6CI,8CI,9CI);1,4-DIACETYLPIPERAZINE;1,1'-(1,4-Piperazinediyl)bisethanone;1,1'-(Piperazine-1,4-diyl)bisethanone;1,1'-(Piperazine-1,4-diyl)diethanone;Piperazine, 1,4-diacetyl;1-(4-acetylpiperazin-1-yl)ethanone
• CAS NO: 18940-57-3
• Molecular Formula: C₈H₁₄N₂O₂
• Molecular Weight: 170.21
• Product Categories: PIPERIDINE
• Mol File: 18940-57-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 365.2 °C at 760 mmHg
• Flash Point: 177.6 °C
• Appearance: /
• Density: 1.126 g/cm³
• Vapor Pressure: 1.6E-05mmHg at 25°C
• Refractive Index: 1.494
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Piperazine, 1,4-diacetyl- (6CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1,4-diacetyl- (6CI,8CI,9CI)(18940-57-3)
• EPA Substance Registry System: Piperazine, 1,4-diacetyl- (6CI,8CI,9CI)(18940-57-3)

Safety Data

• Hazardous Substances Data: 18940-57-3(Hazardous Substances Data)

Usage

General Description

Piperazine, 1,4-diacetyl-, also known as 1,4-diacetylpiperazine, is a chemical compound with the molecular formula C8H14N2O2. It is a derivative of piperazine and is commonly used in the synthesis of pharmaceuticals, especially antihistamines and antipsychotic medications. Piperazine, 1,4-diacetyl- is a white crystalline solid with a faint odor and is soluble in water. It is also used as a building block in the production of pesticides, flame retardants, and other industrial chemicals. Additionally, it has been studied for its potential use as a corrosion inhibitor in metalworking fluids. However, there is limited information available about its specific properties and uses, so further research is needed to fully understand its potential applications.

InChI:InChI=1/C8H14N2O2/c1-7(11)9-3-5-10(6-4-9)8(2)12/h3-6H2,1-2H3

Upstream product

• 110-85-0 piperazine 
• 64-19-7 acetic acid 
• 2466-76-4 N-Acetylimidazole 
• 142-64-3 piperazine dihydrochloride 

Downstream Products

• 6483-50-7 1,4-diethylpiperazine 
• 4164-37-8 1,4-dinitropiperazine 

Relevant articles and documents

CDI-mediated monoacylation of symmetrical diamines and selective acylation of primary amines of unsymmetrical diamines

A highly efficient and green protocol for monoacylation of symmetrical diamines and chemoselective acylation of primary amines of unsymmetrical diamines has been developed.

Microwaves-assisted solvent-free synthesis of N-acetamides by amidation or aminolysis

The preparation of acetamides directly from amines and an acetyl donor under microwaves without any catalyst is described. The inexpensive, solvent free, and fast reaction conditions are the important features of this procedure.