19177-04-9Relevant articles and documents
Isopropylation of m-cresol over mesoporous Al-MCM-41 molecular sieves
Murugesan,Umamaheswari,Palanichamy
, p. 367 - 374 (2002)
A study on the isopropylation of m-cresol with isopropyl alcohol was carried out utilizing Al-MCM-41 molecular sieves with Si/Al ratios of 59:1, 103:1, and 202:1 at 250°-400°C. The products obtained were 2-isopropyl-5-methylphenol (IMP), isopropyl-3-methylphenyl ether (IMPE), and isopropyl-(2-isopropyl-5-methylphenyl) ether (IIMPE). The m-cresol conversion increased till 300°C, after which it decreased. The selectivity of 2-isopropyl-5-methylphenol (IMP) was more than that of the other products. Of the three catalysts studied for isopropylation of m-cresol with isopropyl alcohol in the vapor phase, AI-MCM-41 (59) was more suitable than Al-MCM-41 (103) and Al-MCM-41 (202). The feed ratio of 1:2 was more suitable for better conversion and 100% selectivity to IMP. The study of time on stream indicates the retention of activity even after 10 hr with the feed ratio of 1:4 for nearly 10% conversion. Al-MCM-41 could be a convenient and ecofriendly alternative to the hazardous and highly corrosive mineral acid catalysts for m-cresol isopropylation.
A novel route to produce thymol by vapor phase reaction of m-cresol with isopropyl acetate over Al-MCM-41 molecular sieves
Shanmugapriya,Palanichamy,Arabindoo, Banumathi,Murugesan
, p. 347 - 357 (2004)
Mesoporous Al-MCM-41 (Si/Al = 55 and 104) and Al,Zn-MCM-41 (Si/(Al+Zn)=52) molecular sieves were synthesized hydrothermally. The materials were characterized by XRD, TGA, TPD (pyridine), ICP-AES, nitrogen sorption, and FT-IR techniques. The catalytic performance of these materials was examined in the vapor phase alkylation of m-cresol with isopropyl acetate. The products obtained were thymol, isothymol, 2-isopropyl-5-methylphenyl acetate (2-I-5-MPA), and isopropyl-3-methylphenyl ether (I-3-MPE). The time-on-stream study was carried out over Al-MCM-41(55) at 300°C and WHSV 1.52 h-1 wherein optimum conversion of m-cresol and selectivity to thymol were obtained. The dependence of activity and selectivity on the acid sites and hydrophobic and hydrophilic properties of the catalysts is discussed.
Selective alkylation of m-cresol with isopropyl alcohol under solvent-free conditions
Teodorescu, Florina,Enache, Adrian,Sandulescu, Madalina
, p. 58 - 66 (2017/07/26)
The outcome of the solvent free alkylation of m-cresol with isopropyl alcohol over strong acid resin catalyst has been investigated under microwave irradiation as well as conventional heating. The various reaction parameters like catalyst amount, mole rat
Practical synthesis of aromatic ethers by SNAr of fluorobenzenes with alkoxides
Rodriguez, Juan R.,Agejas, Javier,Bueno, Ana B.
, p. 5661 - 5663 (2007/10/03)
Aromatic fluorines have been substituted by alkoxides in a variety of activated and unactivated aromatic systems.