19780-35-9

Basic information

• Product Name: ETHYL (2R,3R)-2,3-EPOXYBUTYRATE
• Synonyms: ETHYL (2R,3R)-2,3-EPOXYBUTYRATE;ethyl 2,3-epoxybutyrate;Oxiranecarboxylic acid, 3-methyl-, ethyl ester (9CI);Ethyl (2R,3R)-2,3-epoxy-3-methylpropanoate, GC 96%;2,3-Epoxybutyric acid ethyl ester;3-Methyl-2-oxiranecarboxylic acid ethyl ester
• CAS NO: 19780-35-9
• Molecular Formula: C₆H₁₀O₃
• Molecular Weight: 130.1418
• EINECS: 243-300-9
• Product Categories: EPOXYDE;Chiral Compound
• Mol File: 19780-35-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 180.82°C (rough estimate)
• Flash Point: 45.4°C
• Appearance: /
• Density: 1.1066 (rough estimate)
• Vapor Pressure: 6.86mmHg at 25°C
• Refractive Index: 1.4730 (estimate)
• CAS DataBase Reference: ETHYL (2R,3R)-2,3-EPOXYBUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL (2R,3R)-2,3-EPOXYBUTYRATE(19780-35-9)
• EPA Substance Registry System: ETHYL (2R,3R)-2,3-EPOXYBUTYRATE(19780-35-9)

Safety Data

• Hazardous Substances Data: 19780-35-9(Hazardous Substances Data)

Usage

General Description

ETHYL (2R,3R)-2,3-EPOXYBUTYRATE is an organic compound that belongs to the class of epoxides, which are cyclic ethers that contain a three-member ring. It is a colorless liquid with a fruity odor and is commonly used as a flavoring agent in the food and beverage industry. This chemical is also used in the production of fragrances and as a solvent in various industrial applications. It is considered to have low toxicity and is not expected to bioaccumulate in the environment. However, it should still be handled with caution and in accordance with safe handling procedures.

InChI:InChI=1/C6H10O3/c1-3-8-6(7)5-4(2)9-5/h4-5H,3H2,1-2H3

Upstream product

• 75-07-0 acetaldehyde 
• 105-39-5 chloroacetic acid ethyl ester 
• 623-70-1 ethyl (E)-crotonate 
• 75-03-6 ethyl iodide 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 136805-79-3 ethyl 2-<(p-nitrobenzenesulfonyl)oxy>-3-hydroxybutanoate 
• 136805-79-3 ethyl 2-<(p-nitrobenzenesulfonyl)oxy>-3-hydroxybutanoate 
• 623-73-4 diazoacetic acid ethyl ester 
• 113791-25-6 1,3-bis<(trimethylsilyl)oxy>-1-ethoxy-butene 
• 124716-79-6 Ethyl 2-<<(p-nitrophenyl)sulfonyl>oxy>acetoacetate 
• 89490-41-5 (S)-2-Chloro-3-hydroxy-butyric acid ethyl ester 
• 64-17-5 ethanol 
• 10133-06-9 methyl (+/-)-trans-(2,3)-epoxy butanoate 
• 89490-41-5 ethyl 2-chloro-3-hydroxybutanoate 

Downstream Products

• 5405-41-4 ethyl 3-hydroxybutyrate 
• 52089-54-0 ethyl 2-hydroxybutyrate 
• 23000-15-9 2,5-Dimethyl-4-oxazolcarbonsaeure-ethylester 

Relevant articles and documents

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Manganese catalyzed cis-dihydroxylation of electron deficient alkenes with H2O2

A practical method for the multigram scale selective cis-dihydroxylation of electron deficient alkenes such as diethyl fumarate and N-alkyl and N-aryl-maleimides using H2O2 is described. High turnovers (>1000) can be achieved with this efficient manganese based catalyst system, prepared in situ from a manganese salt, pyridine-2-carboxylic acid, a ketone and a base, under ambient conditions. Under optimized conditions, for diethyl fumarate at least 1000 turnovers could be achieved with only 1.5 equiv. of H2O2 with d/l-diethyl tartrate (cis-diol product) as the sole product. For electron rich alkenes, such as cis-cyclooctene, this catalyst provides for efficient epoxidation.

The synthesis of solvent-free glycidic esters from diazoesters and carbonyl compounds catalysed by lanthanide trifiates

The results of the reaction between ethyl diazoacetate and carbonyl compounds catalysed by lanthanide triflates are described. Aldehydes, and α-unsubstituted and α-monosubstituted cyclohexanones react to give the selective formation of α,β-epoxy esters (g