20163-71-7

Basic information

• Product Name: (METHYLSULFONYL)(METHYLTHIO)METHANE
• Synonyms: (METHYLSULFONYL)(METHYLTHIO)METHANE;(Methylsulphonyl)(methylthio)methane, (Methylsulphanyl)(methylsulphonyl)methane, Methyl (methylsulphonyl)methyl sulphide;Methyl (methylthio)methyl sulphone
• CAS NO: 20163-71-7
• Molecular Formula: C₃H₈O₂S₂
• Molecular Weight: 140.22
• Mol File: 20163-71-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (METHYLSULFONYL)(METHYLTHIO)METHANE(CAS DataBase Reference)
• NIST Chemistry Reference: (METHYLSULFONYL)(METHYLTHIO)METHANE(20163-71-7)
• EPA Substance Registry System: (METHYLSULFONYL)(METHYLTHIO)METHANE(20163-71-7)

Safety Data

• Hazardous Substances Data: 20163-71-7(Hazardous Substances Data)

Upstream product

• 74-93-1 methylthiol 
• 2351-74-8 chloromethylsulfonylmethane 
• 1618-26-4 2,4-dithiapentane 
• 33577-16-1 methyl methylsulfinylmethyl sulfide 
• 67-68-5 dimethyl sulfoxide 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 78787-08-3 cyclohexanone dimethyl dithioacetal S,S-dioxide 
• 87228-54-4 2-Methylsulfanylmethanesulfonyl-1-phenyl-ethanone 
• 19916-62-2 2-(Methylsulfonyl)-2-(methylthio)-1-phenylethan-1-one 
• 81236-33-1 (2-Methanesulfonyl-2-methylsulfanyl-ethyl)-benzene 
• 58058-79-0 1-Chloro-4-((E)-2-methanesulfonyl-2-methylsulfanyl-vinyl)-benzene 
• 58058-77-8 ((E)-2-Methanesulfonyl-2-methylsulfanyl-vinyl)-benzene 
• 83831-67-8 1-((E)-2-Methanesulfonyl-2-methylsulfanyl-vinyl)-4-methoxy-benzene 
• 83831-68-9 4-((E)-2-Methanesulfonyl-2-methylsulfanyl-vinyl)-1,2-dimethoxy-benzene 
• 2109-72-0 4-tert-butoxy-1-nitrobenzene 

Relevant articles and documents

Oxidation of Methyl (Methylthio)methyl Sulfoxide

Oxidation of methyl (methylthio)methyl sulfoxide (2) with hydrogen peroxide in acetic acid or methanol produced bis(methylsulfinyl)methane in high yield.Similar results were obtained in oxidation of 2 with ozone, sodium metaperiodate, and m-chloroperbenzoic acid.In contrast, methyl (methylthio)methyl sulfone (4) was exclusively formed when oxidation of 2 with hydrogen peroxide was carried out in methanol in the presence of sodium hydroxide.Furthermore, we established a convenient and efficient method of preparing 4 by oxidation of 2 with potassium permanganate.

Electrosynthesis of sulfonamides from DMSO and amines under mild conditions

With DMSO as the solvent and the precursor of a -SO2Me unit at room temperature, a novel electrochemical oxidization and amination of DMSO with amines was developed for the synthesis of sulfonamides. Our investigations reveal that this transformation may involve a radical process and an electrochemical oxidization of DMSO.

Sulfur containing compounds

This invention is directed to novel and known stufur containing compounds and pharmaceutically acceptable salts thereof that have utility as antifungals and as antiproliferative agents against mammalian cells, in particular cancer cells and most particularly leukemia-derived cells. The invention provides a method for synthesizing certain of the sulfur containing compounds that is more efficient than previously known methods.

Microbiological transformations 36: Preparative scale synthesis of chiral thioacetal and thioketal sulfoxides using whole-cell biotransformations

This work describes the preparative scale enantioselective oxidation of some prochiral dithioacetals and dithioketals to their corresponding chiral monosulfoxides using whole-cell cultures of microorganisms.