20210-14-4

Basic information

• Product Name: 2-(4-Bromobutyl)-2-methyl-1,3-dioxolane
• Synonyms: 2-(4-Bromobutyl)-2-methyl-1,3-dioxolane
• CAS NO: 20210-14-4
• Molecular Formula: C₈H₁₅BrO₂
• Molecular Weight: 223.11
• Mol File: 20210-14-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Bromobutyl)-2-methyl-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Bromobutyl)-2-methyl-1,3-dioxolane(20210-14-4)
• EPA Substance Registry System: 2-(4-Bromobutyl)-2-methyl-1,3-dioxolane(20210-14-4)

Safety Data

• Hazardous Substances Data: 20210-14-4(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Slightly sweet

Usage

Synthesis of pharmaceuticals and other organic compounds

Reagent in organic synthesis

Ability to form strong carbon-carbon bonds

Solubility

High in organic solvents

Toxicity

Relatively low

Importance

Building block for production of various products in pharmaceutical, agricultural, and chemical industries.

Upstream product

• 109-49-9 5-Hexen-2-one 
• 107-21-1 ethylene glycol 
• 1462-03-9 1-methylcyclopentanol 
• 10226-28-5 ethyl 6-methyl-3,4-dihydro-2H-pyran-5-carboxylate 
• 10226-29-6 6-Bromo-2-hexanone 

Downstream Products

• 324012-40-0 (3aS,6aR)-1,3-Dibenzyl-4-(5-oxohexylidene)tetrahydro-1H-thieno[3,4-d]imidazole-2(3H)-one 
• 1505447-92-6 ethyl 1-(4-((7-(2-methyl-1,3-dioxolan-2-yl)hept-2-yn-1-yl)oxy)phenyl)hydrazine-1-carboxylate 
• 1505447-85-7 2-(7-(4-iodophenoxy)hept-5-yn-1-yl)-2-methyl-1,3-dioxolane 
• 1161774-71-5 2-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-4-nitro-2H-[1,2,3]triazole 
• 136429-52-2 nona-6t,8-dien-2-one 
• 30502-73-9 2,8-nonanedione 
• 131711-70-1 1α,3β-dihydroxy-20(S)-(5-hydroxy-5-methylhexyloxy)-9,10-secopregna-5,7,10(19)-triene 
• 160481-86-7 3,3-Dimethyl-1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-2-oxo-cyclohexanecarboxylic acid methyl ester 

Relevant articles and documents

INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN

Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.

AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS

The invention relates to aminotriazole derivatives of formula (I), wherein A, E, R1 and R2 are as defined in the description, their preparation and their use as pharmaceutically active compounds. The compounds are useful for the prevention or treatment of diseases, which respond to the modulation of the ALX receptor such as inflammatory diseases.

An efficient and enantioselective synthesis of d-biotin

An efficient and enantioselective synthesis of d-biotin 1 starting from cis-1,3-dibenzyl-2-imidazo-lidone-4,5-dicarboxylic acid (6) is described. The key steps are the enantioselective reduction of meso-1,2-dicarboxylic thioanhydride 8 to prepare the (3as, 6ar)- thiolactone 9 and the introduction of the C6 side chain at C-2 in 9 via a modified Grignard reaction. This novel synthesis proceeded in six steps to afford 1 with 21% overall yield.