204063-97-8

Basic information

• Product Name: 3-(N-(benzyloxycarbonyl)amino)-3-hydroxyphosphinyl propanoic acid
• Synonyms: 3-(N-(benzyloxycarbonyl)amino)-3-hydroxyphosphinyl propanoic acid
• CAS NO: 204063-97-8
• Molecular Weight: 287.209
• Mol File: 204063-97-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(N-(benzyloxycarbonyl)amino)-3-hydroxyphosphinyl propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N-(benzyloxycarbonyl)amino)-3-hydroxyphosphinyl propanoic acid(204063-97-8)
• EPA Substance Registry System: 3-(N-(benzyloxycarbonyl)amino)-3-hydroxyphosphinyl propanoic acid(204063-97-8)

Safety Data

• Hazardous Substances Data: 204063-97-8(Hazardous Substances Data)

Upstream product

• 121722-22-3 (R,S)-(1-(amino)-2-carboxyethyl)phosphinic acid 
• 501-53-1 benzyl chloroformate 

Relevant articles and documents

A convenient method to synthesize phosphinic peptides containing an aspartyl or glutamyl aminophosphinic acid. Use of the phenyl group as the carboxyl synthon

Many attempts to synthesize AspΨ(PO2CH2)Ala phosphinic pseudodipeptides by Michael addition of aspartyl aminophosphinic acid to ethyl methacrylate have failed. The preparation of such phosphinic peptides was finally achieved starting from a protected PheΨ(PO2CH2)Ala phosphinic building block. The key step is a mild oxidation of the phenyl group to carboxylic acid by use of the ruthenium trichloride-sodium metaperiodate system.