20716-26-1

Basic information

• Product Name: 3-(2-NITRO-PHENYL)-PROPAN-1-OL
• Synonyms: 3-(2-NITRO-PHENYL)-PROPAN-1-OL;2-Nitro-benzenepropanol
• CAS NO: 20716-26-1
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.18854
• Mol File: 20716-26-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(2-NITRO-PHENYL)-PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-NITRO-PHENYL)-PROPAN-1-OL(20716-26-1)
• EPA Substance Registry System: 3-(2-NITRO-PHENYL)-PROPAN-1-OL(20716-26-1)

Safety Data

• Hazardous Substances Data: 20716-26-1(Hazardous Substances Data)

Usage

General Description

3-(2-NITRO-PHENYL)-PROPAN-1-OL is a chemical compound with the molecular formula C9H11NO3. It is a colorless to pale yellow liquid with a molecular weight of 189.19 g/mol. 3-(2-NITRO-PHENYL)-PROPAN-1-OL is commonly used in organic synthesis and as a reagent in chemical reactions. It is also known for its antimicrobial properties and has potential applications in pharmaceuticals and biotechnology. 3-(2-NITRO-PHENYL)-PROPAN-1-OL is considered to be a hazardous chemical and should be handled with care and proper safety precautions.

Upstream product

• 1504-65-0 2-nitrocinnamyl alcohol 
• 24393-59-7 (E)-ethyl 3-(2-nitrophenyl)acrylate 
• 2437-05-0 ethyl 3-(2-nitrophenyl)acrylate 
• 2001-32-3 3-(2-nitrophenyl)propionic acid 

Downstream Products

• 133473-26-4 o-nitrohydrocinnamaldehyde 
• 1119238-24-2 (R)-1,2,3,4-tetrahydroquinolin-3-ol 

Relevant articles and documents

4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES

Compounds of formula (I) for use in the treatment or prophylaxis of a disease, which is a hyperproliferative disease and/or a disorder responsive to induction of cell death, selected from a haematological tumour, a solid tumour and/or metastases thereof, said tumour harbouring a mutant EGFR with exon 19 or 21 mutations, and their use as pharmaceuticals.

Proline catalyzed sequential α-aminooxylation or -amination/reductive cyclization of o-nitrohydrocinnamaldehydes: A high yield synthesis of chiral 3-substituted tetrahydroquinolines

A new sequential organocatalytic method for the synthesis of chiral 3-substituted (X = OH, NH2) tetrahydroquinoline derivatives (THQs) [ee up to 99%, yield up to 87%] based on α-aminooxylation or -amination followed by reductive cyclization of o-nitrohydrocinnamaldehydes has been described. This methodology has been efficiently demonstrated in the synthesis of two important bioactive molecules namely (-)-sumanirole (96% ee) and 1-[(S)-3-(dimethylamino)-3,4-dihydro-6,7-dimethoxy-quinolin-1(2H)-yl]propanone (92% ee). The Royal Society of Chemistry 2013.

Wilkinson's catalyst catalyzed selective hydrogenation of olefin in the presence of an aromatic nitro function: A remarkable solvent effect

Optimal conditions for chlorotris(triphenylphosphine)rhodium(I) (Wilkinson's catalyst) catalyzed selective saturation of a double bond in the presence of a nitro function are developed. Aryl iodide and benzyl ether are also tolerated under these hydrogenation conditions.