20743-50-4

Basic information

• Product Name: 1H-Tetrazole, 1-methyl-5-phenyl-
• Synonyms: 1H-Tetrazole, 1-methyl-5-phenyl-
• CAS NO: 20743-50-4
• Molecular Formula: C₈H₈N₄
• Molecular Weight: 160.18
• Mol File: 20743-50-4.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 276.07°C (rough estimate)
• Flash Point: 143.3°C
• Appearance: /
• Density: 1.2583 (rough estimate)
• Vapor Pressure: 0.000501mmHg at 25°C
• Refractive Index: 1.5872 (estimate)
• CAS DataBase Reference: 1H-Tetrazole, 1-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Tetrazole, 1-methyl-5-phenyl-(20743-50-4)
• EPA Substance Registry System: 1H-Tetrazole, 1-methyl-5-phenyl-(20743-50-4)

Safety Data

• Hazardous Substances Data: 20743-50-4(Hazardous Substances Data)

Usage

General Description

1H-tetrazole, 1-methyl-5-phenyl-, also known as tetsudor, is a chemical compound with the molecular formula C8H7N5. It is a heterocyclic compound composed of a five-membered ring containing four nitrogen atoms and one carbon atom. 1H-Tetrazole, 1-methyl-5-phenyl- is commonly used as a precursor in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of specialty polymers and materials. It is known for its ability to act as a nucleophilic reagent and its versatile applications in organic synthesis. Additionally, it is used as a stabilizer in propellants and explosives due to its high heat and hydrolytic stability. Overall, 1H-tetrazole, 1-methyl-5-phenyl-, has a wide range of industrial and scientific uses due to its unique chemical properties and reactivity.

InChI:InChI=1/C8H8N4/c1-12-8(9-10-11-12)7-5-3-2-4-6-7/h2-6H,1H3

Upstream product

• 88070-48-8 N-methylbenzamide 
• 21737-87-1 N-methyl benzimidoyl chloride 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 77-78-1 dimethyl sulfate 
• 131183-03-4 5-phenyltetrazol-1-yl(trimethylsilyl)methane 
• 120-92-3 cyclopentanone 
• 98-86-2 acetophenone 
• 38792-42-6 N-(chloromethyl)benzamide 
• 616-38-6 carbonic acid dimethyl ester 
• 18039-42-4 5-phenyl-2H-1,2,3,4-tetrazole 
• 74-88-4 methyl iodide 
• 80-11-5 N-methyl-N-nitrosotoluene-p-sulfonamide 
• 74305-28-5 ((CH₃(CH₂)3)3P)Co(HONC(CH₃)C(CH₃)NO)2(N₄C(C₆H₅)) 
• 98-88-4 benzoyl chloride 

Downstream Products

• 131183-03-4 5-phenyltetrazol-1-yl(trimethylsilyl)methane 
• 131183-04-5 1,1-bis(p-tolyl)-2-(5-phenyltetrazol-1-yl)ethanol 
• 24433-71-4 1-ethyl-5-diphenyl-1H-1,2,3,4-tetrazole 
• 120819-50-3 C₉H₁₁N₄⁽¹⁺⁾*CH₃O₄S^(1-) 
• 120836-29-5 C₉H₁₁N₄⁽¹⁺⁾*CH₃O₄S^(1-) 
• 4172-91-2 N-((methylimino)methylene)aniline 
• 131183-00-1 5-phenyltetrazol-1-yldeuteriomethane 
• 69746-32-3 1-methyl-5-(3-nitrophenyl)-tetrazole 
• 101258-12-2 1-methyl-5-(3-aminophenyl)-tetrazole 
• 27770-42-9 methylnitrene 

Relevant articles and documents

An Expeditious Approach to Tetrazoles from Amides Utilizing Phosphorazidates

A novel method was developed for the synthesis of tetrazoles from amides utilizing diphenyl phosphorazidate or bis(p-nitrophenyl) phosphorazidate as both the activator of amide-oxygen for elimination and azide source. Various amides were converted into th

An Environmentally Friendly Method for N-Methylation of 5-Substituted 1H-Tetrazoles with a Green Methylating Reagent: Dimethyl Carbonate

An environmentally friendly method was established for the N-methylation of the 5-substituted 1H-tetrazoles with a green reagent: DMC. DABCO was the optimal catalyst, and hazardous chemicals were avoided in this protocol. A plausible catalytic mechanism is proposed, which consists of a DABCO-activated process and a thermally induced rearrangement of tetrazole carbamates.

Continuous flow generation and reactions of anhydrous diazomethane using a teflon AF-2400 tube-in-tube reactor

A continuous process for generation, separation, and reactions of anhydrous diazomethane in a tube-in-tube reactor was developed. The inner tube of the reactor is made of hydrophobic, gas-permeable Teflon AF-2400. The diazomethane is formed in the inner tube and then diffuses through the permeable membrane into the outer chamber and subsequently reacts in the solution carried within. This technique allows safe and scalable reactions with dry diazomethane to be performed on a laboratory scale.