2078-93-5

Basic information

• Product Name: N-naphthalen-1-yl-2-phenylhydrazinecarbothioamide
• CAS NO: 2078-93-5
• Molecular Formula: C₁₇H₁₅N₃S
• Molecular Weight: 293.3861
• Mol File: 2078-93-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 457.4°C at 760 mmHg
• Flash Point: 230.4°C
• Density: 1.329g/cm³
• Vapor Pressure: 1.49E-08mmHg at 25°C
• Refractive Index: 1.793
• CAS DataBase Reference: N-naphthalen-1-yl-2-phenylhydrazinecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-naphthalen-1-yl-2-phenylhydrazinecarbothioamide(2078-93-5)
• EPA Substance Registry System: N-naphthalen-1-yl-2-phenylhydrazinecarbothioamide(2078-93-5)

Safety Data

• Hazardous Substances Data: 2078-93-5(Hazardous Substances Data)

Upstream product

• 100-63-0 phenylhydrazine 
• 551-06-4 1-isothiocyanatonaphthalene 

Downstream Products

• 120318-40-3 C₁₈H₁₃N₃S 
• 119673-19-7 3-Butylsulfanyl-4-naphthalen-1-yl-1-phenyl-4H-[1,2,4]triazol-1-ium; iodide 

Relevant articles and documents

Bioorthogonal Click and Release Reaction of Iminosydnones with Cycloalkynes

We report the discovery of a new bioorthogonal click-and-release reaction involving iminosydnones and strained alkynes. This transformation leads to two products resulting from the ligation and fragmentation of iminosydnones under physiological conditions. Optimized iminosydnones were successfully used to design innovative cleavable linkers for protein modification, thus opening up new areas in the fields of drug release and target-fishing applications. This click-and-release technology offers the possibility of exchanging tags on proteins for functionalized cyclooctynes under mild and bioorthogonal conditions.