20912-50-9

Basic information

• Product Name: 4-Formylbenzophenone
• Synonyms: 4-Benzoylbenzaldehyde;4-Formylbenzophenone;p-Benzoylbenzaldehyde;p-Formylbenzophenone;Benzaldehyde, 4-benzoyl-
• CAS NO: 20912-50-9
• Molecular Formula: C₁₄H₁₀O₂
• Molecular Weight: 210.23
• Mol File: 20912-50-9.mol
• Article Data: 62

Chemical Properties

• Melting Point: 65-66℃
• Boiling Point: 371.4±25.0 °C(Predicted)
• Appearance: /
• Density: 1.173±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 4-Formylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Formylbenzophenone(20912-50-9)
• EPA Substance Registry System: 4-Formylbenzophenone(20912-50-9)

Safety Data

• Hazardous Substances Data: 20912-50-9(Hazardous Substances Data)

Usage

General Description

4-Formylbenzophenone is an organic compound with the chemical formula C14H10O2. It is a pale yellow solid that is soluble in organic solvents. 4-Formylbenzophenone is commonly used as a photoinitiator in the production of polymers and plastics. It is also used as a building block for organic synthesis, particularly in the production of pharmaceuticals and organic dyes. 4-Formylbenzophenone is known for its ability to absorb UV radiation and promote the rapid polymerization of certain monomers, making it a valuable component in the manufacturing of photopolymerizable materials. Additionally, it has potential applications in the field of photodynamic therapy for the treatment of cancer.

Upstream product

• 31315-53-4 4-(dibromomethyl)benzophenone 
• 1696-17-9 N,N-diethylbenzamide 
• 88682-29-5 4-(1-hydroxy-1-phenylmethyl)benzyl alcohol 
• 52010-95-4 4-(1-hydroxy-1-phenylmethyl)benzaldehyde 
• 87199-17-5 4-formylphenylboronic acid, 
• 65-85-0 benzoic acid 
• 611-95-0 4-carboxybenzophenone 
• 98-88-4 benzoyl chloride 
• 1276635-21-2 4-benzoylbenzaldehyde dimethyl acetal 
• 53178-83-9 (4-(nitromethyl)phenyl)(phenyl)methanone 
• 298-12-4 Glyoxilic acid 
• 135364-97-5 tert-butyl benzoyl(tert-butoxycarbonyl)carbamate 
• 55-21-0 benzamide 
• 3027-03-0 N-acetyl-N-phenylbenzamide 

Downstream Products

• 97250-82-3 [((E)-4-Buta-1,3-dienyl)-phenyl]-phenyl-methanone 
• 81449-01-6 4-(hydroxymethyl)benzophenone 
• 52010-95-4 4-(1-hydroxy-1-phenylmethyl)benzaldehyde 
• 88682-29-5 4-(1-hydroxy-1-phenylmethyl)benzyl alcohol 
• 101033-07-2 (4-[1,3]Dithiolan-2-yl-phenyl)-phenyl-methanone 
• 1000592-63-1 C₂₅H₂₅FN₂O₃S 
• 1276664-79-9 4-(exo-6-bicyclo[3.1.0]hexyl)benzophenone 
• 1276664-81-3 4-(2,3-dimethylcyclopropyl)benzophenone 
• 1276634-95-7 4-(cis-2,3-dimethylcyclopropyl)benzophenone 
• 1276635-07-4 p-benzoylphenyldiazomethane 
• 1276634-93-5 4-(endo-6-bicyclo[3.1.0]hexyl)benzophenone 

Relevant articles and documents

Oxidation of alcohols with nitroxyl radical resins under two-phase conditions

The oxidation of alcohols to carbonyl compounds such as aldehydes and ketones was studied using potassium hexacyanoferrate(III) mediated by nitroxyl radical polystyrene resins as catalyst under organic-aqueous two-phase conditions. Primary alcohols are readily oxidized to the corresponding aldehydes in excellent yield with no overoxidation to carboxylic acids. Secondary alcohols are converted to the corresponding ketones with a much lower efficiency. Oxidative cyclization of 1,4- and 1,5-diols to γ- and δ-lactones, respectively, proceeded nicely. Georg Thieme Verlag Stuttgart.

Aromatization as an Impetus to Harness Ketones for Metallaphotoredox-Catalyzed Benzoylation/Benzylation of (Hetero)arenes

Herein we report ketones as feedstock materials in radical cross-coupling reactions under Ni/photoredox dual catalysis. In this approach, simple condensation first converts ketones into prearomatic intermediates that then act as activated radical sources for cross-coupling with aryl halides. Our strategy enables the direct benzylation/benzoylation of (hetero)arenes under mild reaction conditions with high functional group tolerance.

Self-Assembled 2,3-Dicyanopyrazino Phenanthrene Aggregates as a Visible-Light Photocatalyst

In this study, 2,3-dicyanopyrazino phenanthrene (DCPP), a commodity chemical that can be prepared at an industrial scale, was used as a photocatalyst in lieu of Ru or Ir complexes in C-X (X = C, N, and O) bond-forming reactions under visible-light irradiation. In these reactions, [DCPP]n aggregates were formed in situ through physical π-πstacking of DCPP monomers in organic solvents. These aggregates exhibited excellent photo- and electrochemical properties, including a visible light response (430 nm), long excited-state lifetime (19.3 μs), high excited-state reduction potential (Ered([DCPP]n*/[DCPP]n·-) = +2.10 V vs SCE), and good reduction stability. The applications of [DCPP]n aggregates as a versatile visible-light photocatalyst were demonstrated in decarboxylative C-C cross-coupling, amidation, and esterification reactions.

N-Acyl-5,5-Dimethylhydantoins: Mild Acyl-Transfer Reagents for the Synthesis of Ketones Using Pd-PEPPSI or Pd/Phosphine Catalysts

N-Acyl-hydantoins have emerged as novel acyl-transfer reagents for the synthesis of ketones via selective N-C(O) cleavage. Herein, we report two new protocols for the cross-coupling of N-acyl-5,5-dimethylhydantoins using versatile and readily accessible Pd-PEPPSI or Pd/phosphine catalysts. The acyl Suzuki reactions afford biaryl ketones in good to excellent yields under operationally simple conditions using commercially available, bench- A nd air-stable twisted N-acyl-hydantoins as acyl donors. The method complements and expands on the previous protocol for the cross-coupling of N-acyl-hydantoins (Luo, Z.et al. Org. Process Res. Dev. 2018, 22, 1188).