211693-73-1

Basic information

• Product Name: 2,3-Difluoro-6-nitroaniline
• Synonyms: 2,3-DIFLUORO-6-NITROANILINE;2,3-Difluoro-6-nitroaniline 98%;2,3-Difluoro-6-nitrophenylamine;5,6-Difluoro-2-nitroaniline;2,3-difluoro-6-nitroBenzenamine
• CAS NO: 211693-73-1
• Molecular Formula: C₆H₄F₂N₂O₂
• Molecular Weight: 174.1
• Mol File: 211693-73-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 284.2±35.0℃ (760 Torr)
• Flash Point: 125.7±25.9℃
• Appearance: /
• Density: 1.554±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.00301mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Room temperature.
• PKA: -2.87±0.25(Predicted)
• CAS DataBase Reference: 2,3-Difluoro-6-nitroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Difluoro-6-nitroaniline(211693-73-1)
• EPA Substance Registry System: 2,3-Difluoro-6-nitroaniline(211693-73-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 211693-73-1(Hazardous Substances Data)

Usage

Chemical Properties

light yellow powder

InChI:InChI=1/C6H4F2N2O2/c7-3-1-2-4(10(11)12)6(9)5(3)8/h1-2H,9H2

Upstream product

• 771-69-7 2,3,4-trifluoronitrobenzene 

Downstream Products

• 940351-72-4 2-fluoro-6-nitro-3-phenoxyaniline 
• 211693-75-3 4-Chloro-2,3-difluoro-6-nitroaniline 
• 329926-67-2 2-Fluoro-3-methylsulphanyl-6-nitroaniline 
• 329927-05-1 2-fluoro-3-(isopropylsulphanyl)-6-nitroaniline 
• 626238-73-1 4-bromo-2,3-difluoro-6-nitroaniline 
• 959939-24-3 3-amino-2-fluoro-4-nitrophenol 
• 170432-54-9 2,3-difluoro-N-methyl-6-nitroaniline 
• 1210048-11-5 5-bromo-3,4-difluorobenzene-1,2-diamine 

Relevant articles and documents

PRODUCTION METHOD OF 2,3-DIHALOGENOANILINE

PROBLEM TO BE SOLVED: To provide a production method of 2,3-dihalogenoaniline in a high yield without high-temperature, high-pressure reaction conditions. SOLUTION: A production method of 2,3-dihalogenoaniline includes a step of substituting the 3-halogeno group of a 1,2,3-trihalogeno-4-nitrobenzene with an amino group to obtain 2,3-dihalogeno-6-nitroaniline, making succinic acid to act on the amino group so as to obtain 1-(2,3-dihalogeno-6-nitrophenyl)pyrrolidin-2,5-dione, reducing the 6-nitro group of the obtained 1-(2,3-dihalogeno-6-nitrophenyl)pyrrolidin-2,5-dione to convert into 6-amino group so as to obtain 1-(2,3-dihalogeno-6-aminophenyl)pyrrolidin-2,5-dione (formula (IV)) and reducing the 6-amino group to cleave 2,5-dioxo-1-pyrrolidinyl group so as to induce to an amino group. COPYRIGHT: (C)2016,JPOandINPIT

SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF

The present application relates to novel substituted 5-aminopyrazoles, methods of production thereof, use thereof alone or in combinations for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases.