214139-73-8Relevant articles and documents
Design and fast synthesis of C-terminal duplicated potent C2-symmetric P1/P1'-modified HIV-1 protease inhibitors
Alterman, Mathias,Andersson, Hans O.,Garg, Neeraj,Ahlsén, G?ran,L?vgren, Seved,Classon, Bj?rn,Danielson, U. Helena,Kvarnstr?m, Ingmar,Vrang, Lotta,Unge, Torsten,Samuelsson, Bertil,Hallberg, Anders
, p. 3835 - 3844 (2007/10/03)
An analysis of the X-ray structure of a complex of HIV-1 protease with a linear C2-symmetric C-terminal duplicated inhibitor guided the selection of a series of diverse target compounds. These were synthesized with the objective to identify sui