146285-52-1

Basic information

• Product Name: Ethanimidic acid, 2,2,2-trichloro-, (4-bromophenyl)methyl ester
• CAS NO: 146285-52-1
• Molecular Formula: C9H7BrCl3NO
• Molecular Weight: 331.424
• Mol File: 146285-52-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Ethanimidic acid, 2,2,2-trichloro-, (4-bromophenyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanimidic acid, 2,2,2-trichloro-, (4-bromophenyl)methyl ester(146285-52-1)
• EPA Substance Registry System: Ethanimidic acid, 2,2,2-trichloro-, (4-bromophenyl)methyl ester(146285-52-1)

Safety Data

• Hazardous Substances Data: 146285-52-1(Hazardous Substances Data)

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 545-06-2 trichloroacetonitrile 

Downstream Products

• 1219005-40-9 methyl 2-((4-bromobenzyl)oxy)-3-(tert-butyldimethylsilyloxy)-2-methylpropanoate 
• 278168-71-1 1-bromo-4-(3-phenylprop-2-yn-1-yl)benzene 
• 1018349-44-4 3-(4-bromo-benzyloxy)-2-methyl-propionic acid methyl ester 
• 214139-74-9 N₁,N₆-di[(1S)-2-methyl-1-(methylcarbamoyl)propyl]-(2R,3R,4R,5R)-2,5-di[(4-bromobenzyl)oxy]-3,4-dihydroxyhexanediamide 
• 219596-45-9 (R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3-Hydroxy-10,13-dimethyl-12-(4-pyridin-4-yl-benzyloxy)-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 
• 2116-36-1 1-benzyl-4-bromo-benzene 
• 214139-73-8 2,5-O-bis(4-bromobenzyl)-L-mannaro-1,4:3,6-dilactone 
• 183155-66-0 3-<1-(triphenylmethyl)imidazol-4(5)-yl>propyl 4-bromobenzyl ether 
• 152028-96-1 iodoproxyfan 
• 183155-67-1 3-<1-(triphenylmethyl)imidazol-4(5)-yl>propyl 4-iodobenzyl ether 

Relevant articles and documents

Design and fast synthesis of C-terminal duplicated potent C2-symmetric P1/P1'-modified HIV-1 protease inhibitors

An analysis of the X-ray structure of a complex of HIV-1 protease with a linear C2-symmetric C-terminal duplicated inhibitor guided the selection of a series of diverse target compounds. These were synthesized with the objective to identify sui

A Simple Method for the Preparation of Stainless and Highly Pure Trichloroacetimidates

We describe a method for obtaining various allylic, benzylic, and glucosyl 2,2,2-trichloroacetimidates (TCAIs) as stainless liquids or solids at the crude stage. The general synthetic method for the preparation of TCAIs often leads to stained products, and further purification of crude TCAIs causes decomposition due to their instability. In the described method, we use a solvent that barely dissolves the reactant, providing stainless and sufficiently pure TCAIs without requiring a purification step. Furthermore, the reaction mixture is turbid at the beginning and clear at the end, allowing us to monitor the progress of the reaction visually.

Gold(I)-catalyzed arylmethylation of terminal alkynes

AuCl/AgOTf catalyzes the reaction of terminal alkynes with aryl trichloroacetimidate to afford arylmethylation products in moderate to good yields.