215453-81-9

Basic information

• Product Name: tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(dimethylcarbamoyl)piperazine
• Synonyms: 4-(Dimethylcarbamoyl)piperazine, N1-BOC protected;tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(dimethylcarbamoyl)piperazine;1-Boc-4-dimethylcarbamoylpiperazine
• CAS NO: 215453-81-9
• Molecular Formula: C12H23N3O3
• Molecular Weight: 257.32932
• Mol File: 215453-81-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(dimethylcarbamoyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(dimethylcarbamoyl)piperazine(215453-81-9)
• EPA Substance Registry System: tert-Butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate, 1-(tert-Butoxycarbonyl)-4-(dimethylcarbamoyl)piperazine(215453-81-9)

Safety Data

• Hazardous Substances Data: 215453-81-9(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 506-59-2 N,N-dimethylammonium chloride 
• 530-62-1 1,1'-carbonyldiimidazole 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 124-40-3 dimethyl amine 
• 59878-28-3 tert-butyl 4-(chlorocarbonyl)piperazine-1-carboxylate 
• 79-44-7 N,N-Dimethylcarbamoyl chloride 

Relevant articles and documents

C-3 NOVEL TRITERPENE WITH C-17 AMINE DERIVATIVES AS HIV INHIBITORS

The present invention relates to to C-3 novel triterpene with C-17 amine derivatives of formula (I); or pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, prodrugs, compositions or combination thereof, wherein R1, R2, R3, R4, R5 and 'n' are as defined herein. The present invention also relates to pharmaceutical compositions comprising compounds of formula (I) and process for preparing them, and their use for the treatment of viral diseases and particularly HIV mediated diseases.

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).

2,5-Disubstituted pyridines as potent GPR119 agonists

A series of 2-piperazinyl-5-alkoxypyridines were synthesized and screened against human GPR119 receptor. Through SAR analysis, compounds containing 2-alkylsulfonylpiperazinyl-5-alkoxypyridines were discovered and found to be potent agonists of the human GPR119 receptor.