59878-28-3

Basic information

• Product Name: 4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;1-Piperazinecarboxylic acid, 4-(chlorocarbonyl)-, 1,1-diMethylethyl ester;4-Boc-1-piperazinecarbonyl Chloride;tert-butyl 4-carbonochloridoylpiperazine-1-carboxylate
• CAS NO: 59878-28-3
• Molecular Formula: C₁₀H₁₇ClN₂O₃
• Molecular Weight: 248.70658
• Mol File: 59878-28-3.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 354.5±31.0 °C(Predicted)
• Appearance: /
• Density: 1.231±0.06 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: -0.41±0.70(Predicted)
• CAS DataBase Reference: 4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(59878-28-3)
• EPA Substance Registry System: 4-CHLOROCARBONYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(59878-28-3)

Safety Data

• Hazardous Substances Data: 59878-28-3(Hazardous Substances Data)

Usage

General Description

4-Chlorocarbonyl-piperazine-1-carboxylic Acid Tert-Butyl Ester is a sophisticated chemical compound. This chemical compound is commonly used in the field of organic chemistry for various scientific research and development purposes. One of the key characteristics of this chemical is its piperazine group which is a versatile tool in the world of chemistry, widely used in the manufacture of polymers, resins, and pharmaceuticals. The tert-butyl ester group in its structure also grants specific properties making it highly valuable for chemical synthesis. Detailed information including its physical properties, reactivity, stability, and safety measures, may vary depending on its concentration and specific use and should be thoroughly consulted before handling or usage.

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 75-44-5 phosgene 
• 147081-80-9 N-(1-piperazinyl)-tert-butoxycarboxamide 
• 503-38-8 trichloromethyl chloroformate 

Downstream Products

• 253175-38-1 C₄₁H₄₈N₆O₁₀ 
• 384830-19-7 C₄₄H₅₂N₆O₁₀ 
• 215453-81-9 tert-butyl 4-(dimethylcarbamoyl)piperazine-1-carboxylate 
• 98834-08-3 piperazinocarboxylic acid morpholide 
• 479622-32-7 (2S,3R)-3-(1-{Benzyloxycarbonylamino-[(E)-benzyloxycarbonylimino]-methyl}-piperidin-3-ylmethyl)-4-oxo-1-[4-(4-phenyl-butylcarbamoyl)-piperazine-1-carbonyl]-azetidine-2-carboxylic acid benzyl ester 
• 384830-33-5 4-[methyl-(4-phenyl-butyl)-carbamoyl]-piperazine-1-carbonyl chloride 
• 479622-29-2 4-(4-phenyl-butylcarbamoyl)-piperazine-1-carbonyl chloride 
• 253175-38-1 C₄₁H₄₈N₆O₁₀ 
• 253176-53-3 C₃₅H₄₅N₇O₉ 
• 253176-55-5 C₃₄H₄₃N₇O₉ 

Relevant articles and documents

Piperazine ureido derivative, preparation method thereof and application of piperazine ureido derivative in medicine

The invention relates to piperazine ureido derivatives, a preparation method thereof and an application of the piperazine ureido derivatives in medicine. In particular, the invention relates to piperazine ureido derivatives as shown in a general formula (I), a preparation method thereof, pharmaceutical compositions containing the derivatives, and uses thereof as capsid protein inhibitors, especially in prevention and/or treatment of hepatitis B, influenza, herpes, AIDS and other diseases. Wherein the definition of each group in the general formula (I) is the same as that in the specification.

SUBSTITUTED ALKYNYLENE COMPOUNDS AS ANTICANCER AGENTS

The present invention relates to substituted alkynylene compounds represented by compound of formula (I) pharmaceutically acceptable salts and stereoisomers thereof. The present invention further provides the methods of preparation of compound of formula (I) and therapeutic uses thereof as anti-cancer agents.

SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARAITON AND USE

The present invention provides a compound having the structure: wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5 are other than H; R6 is H, OH, or halogen; and B is a substituted or unsubstituted heterobicycle, wherein when R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is H, R2 is CF3, R3 is H, R4 is CF3, and R5 is H, or R1 is C1, R2 is H, R3 is H, R4 is F, and R5 is H, or R1 is CF3, R2 is H, R3 is F, R4 is H, and R5 is H, or R1 is CF3, R2 is F, R3 is H, R4 is H, and R5 is H, or R1 is C1, R2 is F, R3 is H, R4 is H, and R5 is H, then B is other than or a pharmaceutically acceptable salt thereof.