219714-96-2 Usage
Description
Different sources of media describe the Description of 219714-96-2 differently. You can refer to the following data:
1. Penoxsulam, developed and produced by Dow AgroSciences LLC (Dow AgroSciences), is a trizolo pyrimidine herbicide applied in paddy fields with the widest herbicidal spectrum. It has great effect not only in aquatic weeds control but also in barnyard grass which has resistance to herbicides like quinclorac, propanil and sulfonylurea. With aquatic weeds’ higher resistance, penoxsulam plays a more vital part in weeds control.
2. Penoxsulam is an acetolactate synthase inhibitor herbicide. It provides broad-spectrum control of many annual, biannual, and perennial weeds.
It is used mainly as a post-emergency foliar spray or a granular formulation for the control of broadleaf, sedge, and grass weeds in transplanted, dryseeded, and water-seeded rice. It is also effective against broadleaf weeds in corn, sorghum, wheat, barley and other cereal crops, lawns, golf courses, parks, cemeteries, athletic fields, sod farms, tree and vine crops, range and pasture, roadsides, and other crop and non-crop uses.
As penoxsulam does not bind strongly to either soil or sediments, it tends to be very mobile in both aqueous and terrestrial environments, which makes it a contaminant to groundwater. Penoxsulam is registered for use in Germany, France, Portugal and the USA.
Application
Penoxsulam is a systemic herbicide that moves throughout the plant tissue and prevents plants from producing a necessary enzyme, acetolactate synthase (ALS), which is not found in animals. Susceptible plants will stop growing soon after treatment and become reddish at the tips of the plant. Plant death and decomposition will occur gradually over several weeks to months. Penoxsulam may be used to treat the invasive Eurasian watermilfoil (Myriophyllum spicatum). In other parts of the country, it is valuable as a rotational herbicide against the invasive plant hydrilla (Hydrilla verticillata). Desirable native species that may also be affected include sago pondweed (Stuckenia pectinata), Illinois pondweed (Potamogeton illinoensis), pickerelweed (Pontederia cordata), duckweeds (Lemna spp.) and arrowhead (Sagittaria spp.).
Uses
Different sources of media describe the Uses of 219714-96-2 differently. You can refer to the following data:
1. Penxosulam is a triazolo-pyrimidine sulfonamide herbicide, which is used to control the growth of annual grasses, sedges, and broadleaf weeds in rice agriculture. The compound inhibits the synthesis of acetolactate and targets the biosynthesis of branch-chained amino acids, a metabolic pathway found in plants, fungi, and microorganisms. Acetolactate synthase (ALS) inhibitors are present in most effective herbicides. They are used in agriculture because they show a broad weed control spectrum, crop selectivity, are safe to humans, and can be applied at relatively low usage rates.
2. Herbicide.
Mechanism of action
In the mammalian metabolism studies, penoxsulam was rapidly and almost completely absorbed upon oral administration. There was no evidence of bioaccumulation. Excretion was rapid, but dose and sex dependent as excretion was primarily observed via faeces in males and primarily excreted in urine in females. Penoxsulam was bio-transformed to a large number of metabolites; however the majority of the radioactivity was eliminated as unchanged parent compound.
Degradation
Penoxsulam can be quickly absorbed by the soil. Leachability is weak in most paddy soils. Its adsorption capacity in clay soil and soil with high organic matter is higher than that in light soil and soil with low organic matter content. In soil with pH>8.0, it has the risk of aggravating phytotoxicity. The agent is easy to migrate in the soil and does not stay long-term. Due to the low saturated vapor pressure of the agent, it is not easy to evaporate from the water; in the irrigated rice field, the lookchem half-life of the agent is 2-13d; photolysis and microbial degradation are the main disappearance ways of penoxsulam. It is resistant to hydrolysis in water, but it can quickly disappear after photolysis in shallow water. The photolysis of the aqueous solution is divided into three ways: sulfophthalamide bridge cleavage, the gradual degradation of trimethoprim and its substituents, and sulfophthaleyl photooxidation . This photolysis product can remain for a long time. In paddy soil, anaerobic microbial degradation is an important process for the disappearance of pesticides, and its disappearance speed is as fast as photolysis.
References
[1] Patent: US 20140274711 A1 “Synergistic weed control from applications of penoxsulam and pethoxamid”
[2] http://sitem.herts.ac.uk/aeru/ppdb/en/Reports/512.htm
[3] alyani Paranjape, Vasant Gowariker, V N Krishnamurthy, Sugha Gowariker, The Pesticide Encyclopedia (2014)
Check Digit Verification of cas no
The CAS Registry Mumber 219714-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,9,7,1 and 4 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 219714-96:
(8*2)+(7*1)+(6*9)+(5*7)+(4*1)+(3*4)+(2*9)+(1*6)=152
152 % 10 = 2
So 219714-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)
219714-96-2Relevant articles and documents
HERBICIDAL COMPOSITIONS
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, (2022/03/02)
The present invention provides compositions comprising herbicidally active compounds (A) and (B), where (A) represents one or more compounds of the general formula (I) or agrochemically compatible salts thereof [component (A)], and (B) represents one or more herbicides [component (B)]. The application further relates to a method and to the use of the herbicidal composition according to the invention for controlling harmful plants or for regulating growth.
Preparation method of penoxsulam
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Paragraph 0028; 0031; 0034, (2018/07/15)
The invention provides a preparation method of penoxsulam. The preparation method comprises the following steps: (1) carrying out substitution reaction on m-trifluoromethyl phenol and 2-chloro-1,1-difluoroethane by taking the m-trifluoromethyl phenol as a raw material, thus obtaining m-difluoroethoxy trifluorotoluene (reaction I); (2) enabling the generated m-difluoroethoxy trifluorotoluene to react with sulfuryl fluoride, thus obtaining 2-(2',2'-difluoroethoxy)-6-trifluoromethyl phenyl sulfuryl fluoride (reaction II); (3) enabling the generated 2-(2',2'-difluoroethoxy)-6-trifluoromethyl phenyl sulfuryl fluoride to react with 5,8-dimethoxy-[1,2,4]triazole[1,5-c]pyrimidine-2-amine in a (water-soluble) organic solvent under the action of base, thus obtaining the penoxsulam (reaction III). According to the preparation method provided by the invention, the raw material is cheap and easy to obtain, the technology is safe, the operation is simple, and industrial production is convenient.
An efficient synthesis of 2-(2,2-difluoroethoxy)-6-trifluoromethyl-n-(5,8- dimethoxy-1,2,4-triazolo[1,5-c]pyrimidine-2-yl) benzenesulfonamide: Penoxsulam
Wu, Feifei,Gao, Shiguang,Chen, Zhiyin,Su, Jinyue,Zhang, Dayong
, p. 197 - 200 (2013/07/05)
An efficient nine-step synthesis of 2-(2,2-difluoroethoxy)-6- trifluoromethyl-N-(5,8-dimethoxy-1,2,4-triazolo[1,5-c] - pyrimidine-2-yl) benzenesulfonamide has been developed. The starting material 4-nitro-2-(trifluoromethyl)aniline starting material was converted via 2-bromo-4-amino-6-trifluoromethylaniline and 2-bromo-4-acetamido-6- trifluoromethylbenzenesulfonic acid to 2-bromo-6-trilfuoromethylbenzenesulfonic acid. This was then combined with 2-amino-5,8-dimethoxy-1,2,4-triazolo[1.5-c] pyrimidine to give the target molecule. Compared with the reported method, this approach has advantages in its shorter reaction time, milder reaction conditions and easier purifiction. Moreover, the overall yield has been improved to 22.9% which is twice of that of the reported method.