220630-32-0

Basic information

• Product Name: (2-azido-5-chlorophenyl)methanol
• Synonyms: (2-azido-5-chlorophenyl)methanol
• CAS NO: 220630-32-0
• Molecular Weight: 183.597
• Mol File: 220630-32-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2-azido-5-chlorophenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-azido-5-chlorophenyl)methanol(220630-32-0)
• EPA Substance Registry System: (2-azido-5-chlorophenyl)methanol(220630-32-0)

Safety Data

• Hazardous Substances Data: 220630-32-0(Hazardous Substances Data)

Upstream product

• 37585-25-4 2-amino-5-chlorobenzyl alcohol 

Downstream Products

• 916664-23-8 2-azido 5-chlorobenzaldehyde 
• 1416169-46-4 C₂₂H₁₈ClNO 
• 1416169-42-0 4-chloro-2-methoxymethyl-1-triphenylphosphoranylideneaminobenzene 
• 1416169-52-2 6-chloro-4-methoxy-3,3-diphenyl-3,4-dihydroquinoline 
• 1416169-38-4 1-azido-4-chloro-2-methoxymethylbenzene 
• 1592942-53-4 2-(2-azido-5-chlorophenyl)-N-cyclohexyl-2-(hex-2-ynyloxy)acetamide 
• 1592942-61-4 2-(2-azido-5-chlorophenyl)-N-cyclohexyl-2-(3-phenylprop-2-ynyloxy)acetamide 
• 1630040-94-6 C₁₆H₁₉ClN₄O₃ 
• 1592942-76-1 8-chloro-N-cyclohexyl-3-propyl-4,6-dihydrobenzo[e][1,2,3]triazolo[5,1-c][1,4]oxazepine-6-carboxamide 
• 1592942-80-7 8-chloro-N-cyclohexyl-4,6-dihydrobenzo[e][1,2,3]triazolo[5,1-c][1,4]oxazepine-6-carboxamide 
• 1592942-85-2 8-chloro-N-cyclohexyl-3-phenyl-4,6-dihydrobenzo[e][1,2,3]triazolo[5,1-c][1,4]oxazepine-6-carboxamide 
• 1134435-49-6 O-(2-azido-5-chlorobenzyl)-N-(4-methylphenyl)thiocarbamate 
• 1134435-47-4 O-(2-azido-5-chlorobenzyl)-N-phenylthiocarbamate 
• 220630-49-9 Tris(2-azido-5-chlorobenzyl)amine N-oxide 

Relevant articles and documents

N-butyllithium-mediated reactions of 1-(2-azidoarylmethyl)-1H- benzotriazoles with alkyl halides

(Chemical Equation Presented) Treatment of 1-(2-azidoarylmethyl)-1H- benzotriazoles (6) with n-BuLi (2.5 equiv.) in THF at -78°C, followed by an addition of alkyl halides such as allyl, benzyl, and ethyl bromides with stirring for 2 h at room temperature afforded 2-(dialkylamino)-3-(benzotriazol- 1-yl)-2H-indazoles (8), 3-(benzotriazol-1-yl)-2H-indazoles (9), 2-[(benzotriazol-1-yl)methyl]arylamine (10), and 2-[(benzotriazol-1-yl)(alkyl) methyl]arylamine (11).

Tripod-tripod coupling of triazides with triphosphanes. The synthesis, characterization, and stability in solution of new cage compounds: Chiral macrobicyclic triphosphazides

Several examples of a new type of cage compound, chiral macrobicyclic triphosphazides 15, have been prepared by tripod-tripod coupling of tris(2- azidobenzyl)amines with 1,1,1-tris[(diphenylphosphino)methyl] ethane (triphos). The structure determination of C3 or pseudo-C3-symmetric compounds 15 revealed their propellerlike topology, which accounted for their chirality, the rare Z configuration of the three phosphazide units, and a new conformation of the triphos fragment. Compounds 15 decomposed in solution with a phosphane arm-off mechanism, to give rise to complex mixtures instead of the expected tri-λ5-phosphazenes. The stability of 15 in solution was enhanced by the quaternization of the bridgehead nitrogen atom in the form of an N-oxide. Substituents either in the ortho position to the N termini of the phosphazide units or on the benzylic carbon atoms contributed to a decrease in the stability of macrobicycles 15, and in some cases even prevented their preparation.