220724-82-3

Basic information

• Product Name: (2S,5S)-5-[(Benzyloxycarbonyl-tert-butoxycarbonylmethyl-amino)-methyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester
• Synonyms: (2S,5S)-5-[(Benzyloxycarbonyl-tert-butoxycarbonylmethyl-amino)-methyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester
• CAS NO: 220724-82-3
• Molecular Weight: 520.623
• Mol File: 220724-82-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,5S)-5-[(Benzyloxycarbonyl-tert-butoxycarbonylmethyl-amino)-methyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5S)-5-[(Benzyloxycarbonyl-tert-butoxycarbonylmethyl-amino)-methyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester(220724-82-3)
• EPA Substance Registry System: (2S,5S)-5-[(Benzyloxycarbonyl-tert-butoxycarbonylmethyl-amino)-methyl]-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester(220724-82-3)

Safety Data

• Hazardous Substances Data: 220724-82-3(Hazardous Substances Data)

Upstream product

• 7149-65-7 ethyl (S)-pyroglutamate 
• 220724-81-2 (2S,5S)-5-Formyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-ethyl ester 
• 194594-24-6 (2S)-1-t-butyl 2-ethyl 5-methoxypyrrolidine-1,2-dicarboxylate 
• 144978-35-8 (S)-ethyl N-tert-butoxycarbonylpyroglutamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 220724-83-4 (6S,8aS)-4-Oxo-hexahydro-pyrrolo[1,2-a]pyrazine-2,6-dicarboxylic acid 2-benzyl ester 6-ethyl ester 

Relevant articles and documents

Potent bicyclic lactam inhibitors of thrombin: Part I: P3 modifications

Peptidomimetic inhibitors of general structure 1 have been prepared. Optimization of the binding affinities of these compounds through variation of the P3 hydrophobic residue is described. Selected substituted bicylic lactams displayed interesting pharmacological profiles both in vitro and in vivo.