220952-00-1

Basic information

• Product Name: 3-NITRO-4-PHENYLPYRIDINE
• Synonyms: 3-NITRO-4-PHENYLPYRIDINE;3-Nitro-4-phenypyridine
• CAS NO: 220952-00-1
• Molecular Formula: C₁₁H₈N₂O₂
• Molecular Weight: 200.19
• Mol File: 220952-00-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 324.9 °C at 760 mmHg
• Flash Point: 150.3 °C
• Appearance: /
• Density: 1.252 g/cm³
• Vapor Pressure: 0.000451mmHg at 25°C
• Refractive Index: 1.611
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3-NITRO-4-PHENYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-NITRO-4-PHENYLPYRIDINE(220952-00-1)
• EPA Substance Registry System: 3-NITRO-4-PHENYLPYRIDINE(220952-00-1)

Safety Data

• Hazardous Substances Data: 220952-00-1(Hazardous Substances Data)

Usage

General Description

3-Nitro-4-phenylpyridine is an organic chemical compound classified under the group of organonitrogen compounds, specifically phenylpyridines. It is known by its molecular formula, C11H8N2O2. The structure of this compound includes a pyridine ring, characterized by a six-membered ring with one nitrogen atom, attached to a phenyl group and a nitro group. The presence of the nitro group gives this compound potential to be a nitration reagent in various chemical reactions, particularly in the production of dyes, pharmaceuticals, and agrochemicals. Regarding its safety, it should be handled with care as it may induce harmful effects if improperly handled.

InChI:InChI=1/C11H8N2O2/c14-13(15)11-8-12-7-6-10(11)9-4-2-1-3-5-9/h1-8H

Upstream product

• 939-23-1 p-phenylpyridine 
• 5435-54-1 4-hydroxy-3-nitropyridine 
• 2530-26-9 3-nitropyridine 
• 108-86-1 bromobenzene 
• 626-64-2 pyridin-4-ol 
• 13091-23-1 4-chloro-3-nitropyridine 
• 98-80-6 phenylboronic acid 
• 934-56-5 trimethyl(phenyl)stannane 

Downstream Products

• 165387-78-0 3-amino-2-chloro-4-phenylpyridine 
• 146140-99-0 3-amino-4-phenyl-pyridine 

Relevant articles and documents

Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis

Selective chemistry that modifies the structure of DNA and RNA is essential to understanding the role of epigenetic modifications. We report a visible-light-activated photocatalytic process that introduces a covalent modification at a C(sp3)-H bond in the methyl group of N6-methyl deoxyadenosine and N6-methyl adenosine, epigenetic modifications of emerging importance. A carefully orchestrated reaction combines reduction of a nitropyridine to form a nitrosopyridine spin-trapping reagent and an exquisitely selective tertiary amine-mediated hydrogen-atom abstraction at the N6-methyl group to form an α-amino radical. Cross-coupling of the putative α-amino radical with nitrosopyridine leads to a stable conjugate, installing a label at N6-methyl-adenosine. We show that N6-methyl deoxyadenosine-containing oligonucleotides can be enriched from complex mixtures, paving the way for applications to identify this modification in genomic DNA and RNA.

Photocontrol over cooperative porphyrin self-assembly with phenylazopyridine ligands

The cooperative self-assembly of chiral zinc porphyrins is regulated by a photoresponsive phenylazopyridine ligand (1; see picture). Porphyrin stacks depolymerize into dimers upon axial ligation and the strength of the coordination is regulated by its pho

Cross coupling strategies towards the synthesis of the streptonigrin CD moiety

An efficient route to an appropriate model of the streptonigrin 4- phenylpyridine CD moiety is reported. 4-Chloro-3-nitropyridine was found to be the key precursor and its reactivity in cross coupling reactions was further investigated.