221325-43-5

Basic information

• Product Name: N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester
• Synonyms: N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester
• CAS NO: 221325-43-5
• Molecular Weight: 558.75
• Mol File: 221325-43-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester(221325-43-5)
• EPA Substance Registry System: N-(9-fluorenylmethoxycarbonyl)-O-[(4-amino-α,α-dimethylbenzyl)dimethylsilyl]-L-serine allyl ester(221325-43-5)

Safety Data

• Hazardous Substances Data: 221325-43-5(Hazardous Substances Data)

Upstream product

• 221325-37-7 N-(9-fluorenylmethoxycarbonyl)-O-[(α,α-dimethyl-4-nitrobenzyl)dimethylsilyl]-L-serine allyl ester 
• 221325-34-4 (α,α-dimethyl-4-nitrobenzyl)dimethylsilanol 
• 221325-35-5 chloro(α,α-dimethyl-4-nitrobenzyl)dimethylsilane 
• 118740-38-8 chloro(α,α-dimethylbenzyl)dimethylsilane 
• 136497-85-3 N-(9-fluorenylmethoxycarbonyl)-L-serine allyl ester 
• 144467-97-0 (α,α-dimethylbenzyl)dimethylsilanol 

Downstream Products

• 221325-44-6 N-(9-fluorenylmethoxycarbonyl)-O-[(α,α-dimethyl-4-succin-monoamidobenzyl)dimethylsilyl]-L-serine allyl ester 

Relevant articles and documents

A novel silyl linker: Motif for side chain tethered approach to solid- phase glycopeptide synthesis

In order to facilitate the solid-phase syntheses of protected glycopeptide blocks, we designed a novel silyl linker, which allows the alcoholic side chain (carbohydrate, serine, or threonine) of (glyco-)peptides to link to the solid support. Utilizing this linker, peptide coupling reactions at both the N- and the C-termini were successful. Synthesis of the glycophorin AM fragment corresponding to the N-terminal glycoheptapeptide is demonstrated.