223137-87-9

Basic information

• Product Name: 2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol
• Synonyms: 2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol;2,2',3,3'-Tetrahydro-1,1'-spirobi[indene]-7,7'-diol;2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 99%e.e.;SPINOL
• CAS NO: 223137-87-9
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.31
• Mol File: 223137-87-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 433.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.34
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.70±0.20(Predicted)
• CAS DataBase Reference: 2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol(223137-87-9)
• EPA Substance Registry System: 2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol(223137-87-9)

Safety Data

• Hazardous Substances Data: 223137-87-9(Hazardous Substances Data)

Usage

General Description

2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, also known as spirodiol, is a chemical compound that belongs to the class of spirobiindane derivatives. It is an organic compound with a molecular formula C18H18O2 and a molecular weight of 266.33 g/mol. Spirodiol is a white solid that is sparingly soluble in water but soluble in organic solvents. It is used in organic synthesis as a chiral ligand and as a resolving agent for racemic mixtures. It has been studied for its potential pharmaceutical applications, as it exhibits antioxidant and neuroprotective properties, making it a potentially valuable compound for the development of new drugs.

Upstream product

• 223137-81-3 7,7'-dimethoxy-1,1'-spirobiindane 
• 223137-87-9 (R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 100-83-4 meta-hydroxybenzaldehyde 
• 636601-27-9 (S)-4,4'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 1427054-10-1 1,5-bis(2-bromo-5-hydroxyphenyl)pentan-3-one 
• 1427054-08-7 1,5-bis(3-hydroxyphenyl)pentan-3-one 
• 881915-97-5 (1E,4E)-1,5-bis(3-hydroxyphenyl)penta-1,4-dien-3-one 
• 223137-67-5 1,5-bis(3-methoxyphenyl)-3-pentanone 
• 591-31-1 3-methoxy-benzaldehyde 
• 458533-66-9 (1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one 
• 116836-15-8 1,5-bis(3-methoxyphenyl)-1,4-pentadien-3-one 
• 223137-76-6 4,4'-dibromo-7,7'-dimethoxy-1,1'-spirobiindane 
• 223137-71-1 1,5-bis-(2-bromo-5-methoxyphenyl)-3-pentanone 

Downstream Products

• 223137-87-9 (R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 223137-87-9 2,2′,3,3′-tetrahydro-1,1′-spirobi[indene]-7,7′-diol 
• 500997-68-2 N,N-dicyclohexyl-[(R)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 656233-47-5 (11aR)-(+)-10,11,12,13-tetrahydrodiindeno[7,1-de:1', 7'-fg][1,3,2]dioxaphosphocin-5-bis[(R)-1-phenylethyl]amine 
• 656233-47-5 N,N-di[(R)-1-phenylethyl]-[(S)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 477559-80-1 N,N-diethyl-[(R)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 500997-67-1 [(R)-1,1'-spirobiindane-7,7'-diyl] diisopropylamidophosphite 

Relevant articles and documents

A ligand synthesis of butadiene adhesive

The invention relates to a synthesis method of ligand butadiene adhesive, to 3 - hydroxybenzaldehyde with acetone as the starting material, condensation to obtain the 1, 5 - double-(3 - hydroxy-phenyl) - 1, 4 - isoprene ketone, the 1, 5 - double-(3 - hydr

Chiral oligomers of spiro-salencobalt(III)X for catalytic asymmetric cycloaddition of epoxides with CO2

Several new chiral oligomers of spiro-salenCo(III)X (spiro = 1.1′-spirobiindane-7.7′-diol) complexes have been designed, synthesized, and characterized by nuclear magnetic resonance (NMR), infrared (IR), and elemental analyses, in which, the chiral spiro moieties are first introduced into a scaffold of chiral salenCo catalysts. They were used to catalyze the asymmetric cycloaddition of epoxides with carbon dioxide. Under very mild reaction conditions, a kinetic resolution of racemic epoxides with CO2 was smoothly initiated by these chiral oligomer catalysts with good enantioselectivities, which can be attributed to the match effect between chiral backbones of salen and spiro. High stability and easy recyclability are their major advantages.

CHIRAL COMPOUNDS AND COMPOSITIONS CONTAINING THE SAME

The invention relates to a novel class of compounds useful as chiral dopants, which compounds are available in both enantiomeric forms. Another aspect of the invention relates to such compounds having a enantiomeric excess of one enantiomeric form, which are useful in liquid crystal formulations. Such formulations are advantageous in displays and various other products.