223545-36-6

Basic information

• Product Name: (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-4-trifluoromethanesulfonyloxy-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester
• Synonyms: (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-4-trifluoromethanesulfonyloxy-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester
• CAS NO: 223545-36-6
• Molecular Weight: 567.701
• Mol File: 223545-36-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-4-trifluoromethanesulfonyloxy-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-4-trifluoromethanesulfonyloxy-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester(223545-36-6)
• EPA Substance Registry System: (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-4-trifluoromethanesulfonyloxy-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester(223545-36-6)

Safety Data

• Hazardous Substances Data: 223545-36-6(Hazardous Substances Data)

Upstream product

• 1885-14-9 phenyl chloroformate 
• 223545-30-0 (2R)-2-[(R)-2-methyl-4-pentenyl]-1-(phenoxycarbonyl)-2,3,5,6-tetrahydro-4-pyridone 
• 223545-32-2 (R)-2-((S)-2-Methyl-4-oxo-butyl)-4-oxo-piperidine-1-carboxylic acid phenyl ester 
• 223545-28-6 (R)-2-((R)-2-Methyl-pent-4-enyl)-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid phenyl ester 
• 223545-26-4 (R)-2-((R)-2-Methyl-pent-4-enyl)-2,3-dihydro-1H-pyridin-4-one 
• 126378-42-5 4-methoxy-3-(trisopropylsilyl)pyridine 
• 107735-20-6 [(dimethylphenylsilyl)methyl]magnesium chloride 
• 145100-51-2 N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulphonyl]methanesulphonamide 
• 223545-34-4 (7R,8aR)-7-Methyl-4-oxo-3,4,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester 

Downstream Products

• 223545-42-4 (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-1,2,3,5,6,7,8,8a-octahydro-quinoline 
• 223545-45-7 (4aR,5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-octahydro-quinoline-1-carboxylic acid benzyl ester 
• 223545-39-9 (5R,7R,8aR)-5-[(Dimethyl-phenyl-silanyl)-methyl]-7-methyl-3,5,6,7,8,8a-hexahydro-2H-quinoline-1-carboxylic acid phenyl ester 

Relevant articles and documents

Asymmetric synthesis of all the known phlegmarine alkaloids

The asymmetric synthesis of all four of the known natural phlegmarines and one synthetic derivative has been accomplished in 19-22 steps from 4-methoxy-3-(triisopropylsilyl)pyridine. Chiral N-acylpyridinium salt chemistry was used twice to set the stereoc