22364-28-9

Basic information

• Product Name: 2Bromo-45dimethylacetanilide
• Synonyms: 2Bromo-45dimethylacetanilide
• CAS NO: 22364-28-9
• Molecular Formula: C₁₀H₁₂BrNO
• Molecular Weight: 242.11238
• Product Categories: Anilines, Amides & Amines;Bromine Compounds
• Mol File: 22364-28-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 358.2°C at 760 mmHg
• Flash Point: 170.4°C
• Appearance: /
• Density: 1.413g/cm³
• Vapor Pressure: 2.6E-05mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 2Bromo-45dimethylacetanilide(CAS DataBase Reference)
• NIST Chemistry Reference: 2Bromo-45dimethylacetanilide(22364-28-9)
• EPA Substance Registry System: 2Bromo-45dimethylacetanilide(22364-28-9)

Safety Data

• Hazardous Substances Data: 22364-28-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12BrNO/c1-6-4-9(11)10(5-7(6)2)12-8(3)13/h4-5H,1-3H3,(H,12,13)

Upstream product

• 95-64-7 4-amino-o-xylene 
• 7726-95-6 bromine 
• 2198-54-1 N-(3,4-dimethylphenyl)acetamide 
• 64-19-7 acetic acid 

Downstream Products

• 64835-48-9 N-(4-bromo-3,5-dimethylphenyl)acetamide 
• 15089-80-2 2-acetamido-4,5-dimethylbenzoic acid 
• 24932-48-7 1,2-dibromo-4,5-dimethylbenzene 
• 4612-57-1 2-bromo-4,5-dimethyl-benzoic acid 
• 6514-63-2 2-bromo-4,5-dimethyl-benzonitrile 
• 22364-29-0 2-bromo-4,5-dimethylaniline 

Relevant articles and documents

Nickel(II)- And Silver(I)-Catalyzed C-H Bond Halogenation of Anilides and Carbamates

ortho -C-H bond halogenation of anilides and N -aryl carbamates using easily available N -halosuccinimides (NXS) as the active halogenation reagent in the presence of nickel or silver catalyst has been developed. This method provides a new approach to 2-haloanilides and carbamates, which may serve as starting materials for the synthesis of pharmaceutically and biologically active compounds.

The oxidative bromination and iodination of dimethylacetanilides

The oxidative bromination and iodination of the six dimethylacetanilides have been examined; whereas bromination of 2,4-dimethyl- and 2,6-dimethylacetanilides using potassium bromide, sodium tungstate and peracetic acid gave predominantly the 6- and 4-bro

Process for preparing pyrimidine derivatives

The present invention provides a process for preparing a 5,6-dihydro-3H-pyrimidin-4-one derivatives which comprises the steps of (a) dehydrating a N-acyl beta amino acid in the presence of a dehydration agent and an organic solvent for a sufficient period of time and under suitable temperature and pressure conditions to form an oxazone (b) adding a carboxylic acid and a primary amine salt of a carboxylic acid to said oxazone to form a mixture, (c) distilling azeotropically said mixture for a suitable period of time and under suitable temperature and pressure conditions to substantially remove said dehydration agent and said organic solvent, and (d) heating the product of step (c) for a sufficient period of time and under suitable temperature and pressure conditions to form said pyrimidin derivatives.