24932-48-7

Basic information

• Product Name: 4,5-DIBROMO-O-XYLENE
• Synonyms: 1,2-DIBROMO-4,5-DIMETHYLBENZENE;4,5-DIBROMO-O-XYLENE;4,5-DIBROMO-1,2-DIMETHYLBENZENE;1,2-Dibromo-4,5-dimethylbenzene 98+%;1,2-DiMethyl-4,5-dibroMobenzene;2-Dibromo-4,5-dimethylbenzene
• CAS NO: 24932-48-7
• Molecular Formula: C₈H₈Br₂
• Molecular Weight: 263.96
• Product Categories: Halides;Phenyls & Phenyl-Het;Phenyls & Phenyl-Het
• Mol File: 24932-48-7.mol
• Article Data: 26

Chemical Properties

• Melting Point: 85-89 °C(lit.)
• Boiling Point: 278 °C
• Flash Point: 138.7 °C
• Appearance: /
• Density: 1.7485 (rough estimate)
• Vapor Pressure: 0.00694mmHg at 25°C
• Refractive Index: 1.6146 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• BRN: 2206183
• CAS DataBase Reference: 4,5-DIBROMO-O-XYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIBROMO-O-XYLENE(24932-48-7)
• EPA Substance Registry System: 4,5-DIBROMO-O-XYLENE(24932-48-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 24932-48-7(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Uses

Different sources of media describe the Uses of 24932-48-7 differently. You can refer to the following data:
1. 1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
2. 1,2-Dibromo-4,5-dimethylbenzene can be used in the synthesis of alkylamino zinc(II)phthalocyanines, with potential application as photosensitizers in photodynamic therapy. It can also be used in the synthesis of 1,2-dibromo-4,5-bis(dibromomethyl)benzene via reaction with azobisisobutyronitrile.

General Description

1,2-Dibromo-4,5-dimethylbenzene can be synthesized via bromination of o-xylene.

InChI:InChI=1/C8H8Br2/c1-5-3-7(9)8(10)4-6(5)2/h3-4H,1-2H3

Upstream product

• 95-47-6 o-xylene 
• 7726-95-6 bromine 
• 7553-56-2 iodine 
• 75-16-1 methylmagnesium bromide 
• 529502-50-9 1,2-dibromo-4,5-diiodobenzene 
• 2198-54-1 N-(3,4-dimethylphenyl)acetamide 
• 22364-28-9 N-(2-bromo-4,5-dimethylphenyl)acetamide 
• 22364-29-0 2-bromo-4,5-dimethylaniline 
• 583-71-1 4-bromo-o-xylene 

Downstream Products

• 78823-49-1 1,2-dibromo-3,6-diiodo-4,5-dimethylbenzene 
• 216433-16-8 1,2-dibromo-4-bromomethyl-5-methylbenzene 
• 95-47-6 o-xylene 
• 95-63-6 1,2,4-Trimethylbenzene 
• 95-93-2 1,2,4,5-tetramethylbenzene 
• 1309381-72-3 C₂₈H₂₆P₂ 
• 1309381-72-3 C₂₈H₂₆P₂ 
• 1309381-74-5 2,3,7,8-tetramethyl-5,10-diphenyl-5,10-dihydrophosphanthrene dioxide 
• 1309381-71-2 2,3,7,8-tetramethyl-5,10-diphenyl-5,10-dihydrophosphanthrene dioxide 
• 151293-11-7 5,6-dimethyl-2-phenylbenzo[d]oxazole 
• 1091603-68-7 2,3,6,7-tetramethyl-9,10-diphenylphenanthrene 
• 31776-14-4 6,7-dimethyl-1-naphthol 

Relevant articles and documents

Peripherally octamethyl zinc(II) phthalocyanines with various axial substituents

A series of zinc(II) phthalocyanine complexes peripherally octa-substituted by methyl groups and with axially ligated N-donor ligands, (Zn(Me)8Pc-L, where L is pyridine (4), 3-methylpyridine (5), 3,4-lutidine (6) and 3,5-lutidine (7)), was synt

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Multisubstituted C2-symmetric ansa -metallocenes bearing nitrogen heterocycles: Influence of substituents on catalytic properties in propylene polymerization at higher temperatures

In this work we systematically studied the effects of modifications of substituents on the performance of the isospecific zirconocene-based catalyst family, Me2Si(2-Alk-4-(N-carbazolyl)Ind)ZrX2 (X = Cl, Me), wherein the progenitor was shown to be particul

Subnaphthalocyanine triimides: Potential three-dimensional solution processable acceptors for organic solar cells

Subnaphthalocyanine triimides (SubNcTIs) as solution processable electron acceptors were designed and synthesized by introducing three electron-withdrawing imide groups to subnaphthalocyanines. Their solubility and crystallinity could be adjusted convenie