2267-30-3

Basic information

• Product Name: 3-(Fluoromethyl)fluorobenzene
• Synonyms: 3-(Fluoromethyl)fluorobenzene;1-Fluoro-3-(fluoromethyl)benzene;m-Fluorobenzyl fluoride
• CAS NO: 2267-30-3
• Molecular Formula: C₇H₆F₂
• Molecular Weight: 128.1193464
• Mol File: 2267-30-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(Fluoromethyl)fluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Fluoromethyl)fluorobenzene(2267-30-3)
• EPA Substance Registry System: 3-(Fluoromethyl)fluorobenzene(2267-30-3)

Safety Data

• Hazardous Substances Data: 2267-30-3(Hazardous Substances Data)

Upstream product

• 456-41-7 1-(Bromomethyl)-3-fluorobenzene 
• 352-70-5 m-Fluorotoluene 
• 456-42-8 m-fluorobenzyl chloride 
• 456-47-3 3-fluoro-benzenemethanol 

Relevant articles and documents

Competitive fluorination on methyl-group and benzene-ring during the anodic fluorination of fluorotoluenes in Et4NF · mHF

Electrochemical fluorinations of 2-fluorotoluene (2a), 3-fluorotoluene (3a) and 4-fluorotoluene (4a) in neat Et4NF · mHF (Et = C2H5, m = 3.5 or 4.0) were carried out on a platinum anode. The fluorination of 2a, 3a and 4a occurred competitively both on the side-chain (formation of monofluoromethylfluorobenzenes) and on the benzene-ring (formation of methyltrifluoro-1,4-cyclohexadienes). These results are explained by the facility of proton elimination from the methyl groups of the radical cations which have been formed by the anodic one-electron transfer reactions of 2a, 3a and 4a. A cyclic voltammogram of 4a showed three anodic current peaks which correspond to the oxidation of 4a, 1-fluoromethyl-4-fluorobenzene (4b) and 1-difluoromethyl-4-fluorolbenzene (4c). On the other hand, voltammograms of 2a and 3a showed two anodic current peaks and no difluoromethylfluorobenzenes was obtained during the fluorination of 2a and 3a.

MECHANISMS OF FREE-RADICAL REACTIONS. XX. REACTIVITY IN THE FREE-RADICAL HALOGENATION REACTIONS OF ARYLFLUOROALKANES

The free-radical chlorination and bromination of meta- and para-substituted benzyl fluorides and 1,1-difluoro-2-phenylethane and also the chlorination of 1-fluoro-2-arylethanes by phenylchloroiodonium chloride and the bromination of meta- and para-substituted benzyl bromides were studied by the method of competing reactions.In all cases a good correlation is observed between log krel and the Brown ?+ constants.In cases where change in the reactivity in the transition from one reaction series to another is due mainly to the polar effect of the substituent whilethe selectivity is measured in relation to the polar effect direct relationships are observed between the reactivity and the selectivity.