22824-20-0

Basic information

• Product Name: Benzenebutanoic acid, 2-nitro-, methyl ester
• CAS NO: 22824-20-0
• Molecular Formula: C11H13NO4
• Molecular Weight: 223.229
• Mol File: 22824-20-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, 2-nitro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, 2-nitro-, methyl ester(22824-20-0)
• EPA Substance Registry System: Benzenebutanoic acid, 2-nitro-, methyl ester(22824-20-0)

Safety Data

• Hazardous Substances Data: 22824-20-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1701-57-1 2,3,4,5-tetrahydro-1Hbenzo[b]azepine 
• 67857-97-0 4-(2-nitrophenyl)-n-butyric acid 
• 5600-62-4 4-(4-nitrophenyl)butanoic acid 
• 609-73-4 o-nitroiodobenzene 
• 7440-66-6 zinc 
• 88-72-2 1-methyl-2-nitrobenzene 
• 292638-85-8 acrylic acid methyl ester 
• 1821-12-1 4-Phenylbutyric acid 

Downstream Products

• 46320-17-6 4-(2-aminophenyl)butanoic acid methyl ester 
• 113849-32-4 4-(2,4-Diamino-phenyl)-butyric acid methyl ester 
• 113849-34-6 methyl 4-phenyl>butyrate 
• 113849-35-7 methyl 4-phenyl>butyrate 
• 943345-27-5 4-(2-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid methyl ester 
• 943345-28-6 4-(2-{[5-(4-Methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid 

Relevant articles and documents

Deconstructive di-functionalization of unstrained, benzo cyclic amines by C-N bond cleavage using a recyclable tungsten catalyst

With H2WO4 as the catalyst and H2O2 as the oxidant, we herein report a deconstructive difunctionalization of the C-N bond in unstrained, benzo cyclic amines to generate an ester group and nitro group simultaneously. The preliminary mechanistic studies suggested that the corresponding hydroxamic acid is the key intermediate for this transformation. Importantly, with the utilization of this transformation, we achieved an interesting approach for the ring contraction of quinoline to indole, an example of scaffold hopping in a hetero-aromatic system.

Histone deacetylase inhibitors

This invention relates to novel Histone deacetylases inhibitors. Also disclosed is a method for treating mucositis or cancer with these inhibitors.

Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient

A carboxylic acid derivative of formula (1) wherein R1 is COOH, COOR6 etc.; A is alkylene etc.; R2 is alkyl, alkenyl, alkynyl etc.; B is carbocyclic ring or heterocyclic ring; R4 is alkyl, cycloalkyl etc.; Rsup