22854-75-7

Basic information

• Product Name: N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine
• Synonyms: N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine
• CAS NO: 22854-75-7
• Molecular Weight: 858.899
• Mol File: 22854-75-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine(22854-75-7)
• EPA Substance Registry System: N,N',N'',N'''-tetra(benzyloxycarbonyl)neamine(22854-75-7)

Safety Data

• Hazardous Substances Data: 22854-75-7(Hazardous Substances Data)

Upstream product

• 15446-43-2 neamine tetrahydrochloride 
• 501-53-1 benzyl chloroformate 
• 41547-94-8 4-O-(2,6-di-deoxy-α-D-2,6-di-amine-glucopyranosyl)-2-deoxy-streptamine hydrochloride 
• 3947-65-7 neomycin A 
• 119-04-0 neomycin B 

Downstream Products

• 1198767-80-4 dibenzyl (3aS,4R,5S,7R,7aS)-4-oxohexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-5,7-diyldicarbamate 
• 1267385-38-5 dibenzyl (3aR,4S,5S,7R,7aS)-4-hydroxy-4-vinylhexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-5,7-diyldicarbamate 
• 1267385-40-9 dibenzyl (3aR,4S,5S,7R,7aS)-4-allyl-4-hydroxyhexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-5,7-diyldicarbamate 
• 1261084-70-1 dibenzyl (3aR,4S,5S,7R,7aS)-4-(but-3-enyl)-4-hydroxyhexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-5,7-diyldicarbamate 
• 82509-76-0 dibenzyl (3aS,4R,5S,7R,7aS)-4-hydroxyhexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-5,7-diyldicarbamate 
• 183660-36-8 Acetic acid (1S,2S,3R,4S,6R)-4,6-bis-benzyloxycarbonylamino-3-[(2R,3R,4R,5R,6R)-4,5-diacetoxy-3-benzyloxycarbonylamino-6-(benzyloxycarbonylamino-methyl)-tetrahydro-pyran-2-yloxy]-2-(2-oxo-ethoxy)-cyclohexyl ester 
• 183660-34-6 Acetic acid (1S,2S,3R,4S,6R)-2-allyloxy-4,6-bis-benzyloxycarbonylamino-3-[(2R,3R,4R,5R,6R)-4,5-diacetoxy-3-benzyloxycarbonylamino-6-(benzyloxycarbonylamino-methyl)-tetrahydro-pyran-2-yloxy]-cyclohexyl ester 

Relevant articles and documents

Designed spiro-bicyclic analogues targeting the ribosomal decoding center

The bacterial ribosome represents the confirmed biological target for many known antibiotics that interfere with bacterial protein synthesis. Aminoglycosides represent a lead paradigm in RNA molecular recognition and constitute ideal starting points for t

Design of novel antibiotics that bind to the ribosomal acyltransfer site

The structure of neamine bound to the A site of the bacterial ribosomal RNA was used in the design of novel aminoglycosides. The design took into account stereo and electronic contributions to interactions between RNA and aminoglycosides, as well as a ran