22895-19-8

Basic information

• Product Name: DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE
• Synonyms: DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE;DIMETHYL 4-METHOXYPHTHALATE;4-Methoxyphthalsaeure-methylester
• CAS NO: 22895-19-8
• Molecular Formula: C₁₁H₁₂O₅
• Molecular Weight: 224.21
• Mol File: 22895-19-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 74-75 °C(Solv: hexane (110-54-3); ethyl ether (60-29-7))
• Boiling Point: 140 °C0.1 mm Hg(lit.)
• Flash Point: 109 °C
• Appearance: /
• Density: 1.225 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.000985mmHg at 25°C
• Refractive Index: n20/D 1.531
• BRN: 2373838
• CAS DataBase Reference: DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE(22895-19-8)
• EPA Substance Registry System: DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE(22895-19-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 22895-19-8(Hazardous Substances Data)

Usage

General Description

DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE is a chemical compound that is commonly used in the synthesis of pharmaceuticals and agrochemicals. It is derived from the esterification of 4-Methoxybenzene-1,2-dicarboxylic acid with methanol. DIMETHYL 4-METHOXYBENZENE-1,2-DICARBOXYLATE is often used as an intermediate in the production of various organic compounds, and it also has potential applications in the field of material science. Additionally, it is important to handle this chemical with care, as it can be harmful if ingested or inhaled, and can cause irritation to the skin and eyes.

InChI:InChI=1/C11H12O5/c1-14-7-4-5-8(10(12)15-2)9(6-7)11(13)16-3/h4-6H,1-3H3

Upstream product

• 67-56-1 methanol 
• 87639-57-4 4-bromophthalic Acid Dimethyl Ester 
• 610-35-5 4-hydroxyphthalic acid 
• 17573-92-1 3-methoxy-thiophene 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 22479-95-4 dimethyl 4-hydroxyphthalate 
• 74-88-4 methyl iodide 
• 83027-08-1 (1E)-1,3-dimethoxy-1,3-butadiene 
• 108153-40-8 4-methoxy-6-oxo-6H-pyran-2-carboxylic acid methyl ester 
• 922-67-8 propynoic acid methyl ester 
• 867-89-0 1-dimethylamino-1-methoxyethylene 
• 17412-11-2 dimethyl pyridazine-4,5-dicarboxylate 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 36132-96-4 1,2-bis(bromomethyl)-4-methoxybenzene 
• 50727-04-3 4-methoxyphthalimide 
• 60889-21-6 6-methoxyphthalazin-1-(2H)-one 
• 4741-62-2 5-methoxyisobenzofuran-1(3H)-one 
• 65399-12-4 2-hydroxymethyl-4-methoxy-benzoic acid 
• 28281-76-7 5-methoxyisobenzofuran-1,3-dione 
• 1603818-42-3 dimethyl (2S,4S)-2-(benzyloxy)-4-(5-methoxy-1,3-dioxoisoindolin-2-yl)-2-phenylcyclopentane-1,1-dicarboxylate 
• 1885-13-8 4-methoxyphthalic acid 
• 1007455-12-0 2-benzyl-5-methoxyisoindoline-1,3-dione 

Relevant articles and documents

Preparation and Diels-Alder Reaction of (1E)-1,3-Dimethoxybutadiene

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NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel brominated furanone derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient, wherein the novel brominated furanone derivative or a pharmaceutically acceptable 5 salt thereof according to the present invention exhibits a quorum sensing inhibitory activity of bacteria and also can effectively inhibit the formation of biofilm of bacteria, and thus can be used as a pharmaceutical composition containing the same as an active ingredient, thereby having an effect of being useful, 10 for example, for periodontal diseases such as gingivitis and periodontitis, oral diseases, and the like.

Dynamic kinetic asymmetric [3 + 2] annulation reactions of aminocyclopropanes

We report the first example of a dynamic kinetic asymmetric [3 + 2] annulation reaction of aminocyclopropanes with both enol ethers and aldehydes. Using a Cu catalyst and a commercially available bisoxazoline ligand, cyclopentyl- and tetrahydrofurylamines were obtained in 69-99% yield and up to a 98:2 enantiomeric ratio using the same reaction conditions. The method gives access to important enantio-enriched nitrogen building blocks for the synthesis of bioactive compounds.