87639-57-4

Basic information

• Product Name: DIMETHYL 4-BROMOPHTHALATE
• Synonyms: DIMETHYL 4-BROMOPHTHALATE;1,2-Benzenedicarboxylic acid, 4-broMo-, 1,2-diMethyl ester
• CAS NO: 87639-57-4
• Molecular Formula: C₁₀H₉BrO₄
• Molecular Weight: 273.08
• Mol File: 87639-57-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 33-35 °C
• Boiling Point: 305.1 °C at 760 mmHg
• Flash Point: 138.3 °C
• Appearance: /
• Density: 1.505g/cm³
• Vapor Pressure: 0.00084mmHg at 25°C
• Refractive Index: 1.546
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: DIMETHYL 4-BROMOPHTHALATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL 4-BROMOPHTHALATE(87639-57-4)
• EPA Substance Registry System: DIMETHYL 4-BROMOPHTHALATE(87639-57-4)

Safety Data

• Hazardous Substances Data: 87639-57-4(Hazardous Substances Data)

Usage

General Description

DIMETHYL 4-BROMOPHTHALATE is a chemical compound with the molecular formula C10H9BrO4. It is a derivative of phthalic acid and is commonly used in the synthesis of various organic compounds. DIMETHYL 4-BROMOPHTHALATE is frequently used as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. It is a white crystalline solid with a sharp, unpleasant odor, and it is soluble in organic solvents such as ethanol and acetone. DIMETHYL 4-BROMOPHTHALATE is also known for its use as a reagent in organic chemical reactions, particularly in the esterification and acylation processes. However, it is important to handle this compound with caution as it is considered to be harmful if ingested, inhaled, or comes into contact with the skin.

InChI:InChI=1/C10H9BrO4/c1-14-9(12)7-4-3-6(11)5-8(7)10(13)15-2/h3-5H,1-2H3

Upstream product

• 86-90-8 4-bromophthalic anhydride 
• 67-56-1 methanol 
• 6968-28-1 4-bromophthalic acid 

Downstream Products

• 865354-06-9 4-(3-fluorophenylethynyl)dimethyl phthalate 
• 22895-19-8 dimethyl 4-methoxyphtalate 
• 36978-37-7 3,3',4,4'-biphenyltetracarboxylic acid tetramethyl ester 
• 36978-36-6 2,3,3',4'-biphenyltetracarboxylic acid tetramethyl ester 
• 131-11-3 phthalic acid dimethyl ester 

Relevant articles and documents

TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE

The present disclosure relates to bifunctional compounds, which find utility as modulators of tan protein. In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a VHL or cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds tan protein, such that tan protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of tan. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of tan protein. Diseases or disorders that result from aggregation or accumulation of tan protein are treated or prevented with compounds and compositions of the present disclosure.

TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE

This disclosure relates to bivalent compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the bivalent compounds, and to methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such bivalent compounds.

TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE

Bivalent compounds, compositions comprising one or more of the bivalent compounds, and methods of use the bivalent compounds for the treatment of certain disease in a subject in need thereof are provided. Methods for identifying such bivalent compounds are provided, either.