23023-35-0

Basic information

• Product Name: 3-PHENYL-ISOQUINOLIN-1-YLAMINE
• Synonyms: 3-PHENYL-ISOQUINOLIN-1-YLAMINE
• CAS NO: 23023-35-0
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.27
• Mol File: 23023-35-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 424.2°Cat760mmHg
• Flash Point: 240°C
• Appearance: /
• Density: 1.194g/cm³
• Vapor Pressure: 2.1E-07mmHg at 25°C
• Refractive Index: 1.697
• CAS DataBase Reference: 3-PHENYL-ISOQUINOLIN-1-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYL-ISOQUINOLIN-1-YLAMINE(23023-35-0)
• EPA Substance Registry System: 3-PHENYL-ISOQUINOLIN-1-YLAMINE(23023-35-0)

Safety Data

• Hazardous Substances Data: 23023-35-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H12N2/c16-15-13-9-5-4-8-12(13)10-14(17-15)11-6-2-1-3-7-11/h1-10H,(H2,16,17)

Upstream product

• 83576-26-5 5-phenyl-1-(1-phenylvinyl)-1H-tetrazole 
• 751479-61-5 benzyl(3-phenylisoquinolin-1-yl)amine 
• 7115-13-1 3-phenyl-2H-isoquinolin-1-one 
• 55150-54-4 1-chloro-3-phenylisoquinoline 
• 2170-09-4 N,2-dimethylbenzamide 
• 100-47-0 benzonitrile 
• 536-74-3 phenylacetylene 
• 96-09-3 styrene oxide 
• 3759-28-2 (2-cyanophenyl)acetonitrile 
• 98-80-6 phenylboronic acid 
• 1039765-06-4 N-benzyl-2-chlorobenzenecarboximidamide 
• 873-32-5 2-Chlorobenzonitrile 
• 529-19-1 2-Methylbenzonitrile 
• 7154-66-7 2-bromobenzoic acid chloride 

Downstream Products

• 105516-75-4 N-methyl-3-phenylisoquinolin-1-amine 
• 82071-21-4 n,3-diphenylisoquinolin-1-amine 

Relevant articles and documents

Silver(I)- and Base-Mediated [3 + 3]-Cycloaddition of C,N-Cyclic Azomethine Imines with Aza-oxyallyl Cations

A silver(I) and base-mediated [3 + 3]-cycloaddition reaction of in situ generated C,N-cyclic azomethine imines with in situ formed aza-oxyallyl cations is reported. This one-pot cycloaddition process shows broad substrate scope an excellent functional group tolerance and provides the corresponding biologically important isoquinoline-fused triazines in good to excellent yields.

Heterogeneous gold(III)-catalyzed tandem cyclization of 2-alkynylbenzamides with ammonium acetate toward 1-aminoisoquinolines

Heterogeneous tandem cyclization of 2-alkynylbenzamides with ammonium acetate is achieved in acetonitrile at 85 °C using a magnetic nanoparticles-immobilized bipy-gold(III) complex and AgSbF6 as catalysts to afford a variety of 1-aminoisoquinoline derivatives in moderate to high yields. This heterogeneous gold catalyst can be easily recovered from the reaction mixture by simply applying an external magnetic field and can be recycled at least seven times without any apparent loss of catalytic activity.

Nickel-Catalyzed Annulation of o-Haloarylamidines with Aryl Acetylenes: Synthesis of Isoquinolone and 1-Aminoisoquinoline Derivatives

An efficient method for the synthesis of substituted 1(2H)-isoquinolone derivatives via nickel-catalyzed annulation of substituted 2-halobenzamidines with aryl alkynes in the presence of water is described. Benzo[4,5]imidazo[2,1-a]isoquinolines were formed as the dominated products when dry dimethyl sulfoxide was used as the solvent. Furthermore, when benzyl substituted amidines were used as the substrates, debenzylation reaction occured to provide various 1-aminoisoquinoline products. (Figure presented.).