23028-17-3

Basic information

• Product Name: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid
• Synonyms: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid;3-(3,4-Dihydroxyphenyl)lactic acid;3,4-dihydroxyphenyllactic acid;3,4-DIHYDROXYPHENYLLACTIC ACID SODIUM SALT 90%;2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid;2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid;3-(3,4-Dihydroxyphenyl)-2-hydroxypropionic acid;α,3,4-Trihydroxybenzenepropanoic acid
• CAS NO: 23028-17-3
• Molecular Formula: C₉H₁₀O₅
• Molecular Weight: 198.05
• Mol File: 23028-17-3.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 481.469 °C at 760 mmHg
• Flash Point: 259.091 °C
• Appearance: /
• Density: 1.546±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 4.91E-10mmHg at 25°C
• Refractive Index: 1.649
• PKA: 3.82±0.10(Predicted)
• CAS DataBase Reference: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(23028-17-3)
• EPA Substance Registry System: 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid(23028-17-3)

Safety Data

• Hazardous Substances Data: 23028-17-3(Hazardous Substances Data)

Usage

General Description

3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid, also known as dihydroxyphenyllactic acid, is a chemical compound with a molecular formula C9H10O5. It is a derivative of lactic acid and belongs to the class of phenolic acids. 3-(3,4-dihydroxyphenyl)-2-hydroxy-propanoic acid is a colorless crystalline solid that is commonly found in various plant sources, including fruits, vegetables, and nuts. It exhibits antioxidant properties and has been studied for its potential health benefits, including anti-inflammatory and neuroprotective effects. Its presence in dietary sources and potential biological activities make it an important molecule of interest in the fields of nutrition and medicine.

InChI:InChI=1/C9H10O5/c1-9(14,8(12)13)5-2-3-6(10)7(11)4-5/h2-4,10-11,14H,1H3,(H,12,13)

Upstream product

• 4228-66-4 L-586462 
• 1174920-56-9 clinopodic acid C 
• 20283-92-5 (R)-(+)-rosmarinic acid 
• 55757-13-6 salvianolic acid B 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 64521-33-1 2-acetylamino-3-(3,4-dihydroxyphenyl)-propenoic acid 
• 87950-39-8 (Z)-4-((2-methyl-5-oxooxazol-4(5H)-ylidene)methyl)-1,2-phenylene diacetate 
• 457893-80-0 (-)-(R)-methyl 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate 

Downstream Products

• 179462-74-9 rosmarinic acid 
• 20283-92-5 (R)-(+)-rosmarinic acid 
• 179128-91-7 3-(3,4-Bis-allyloxy-phenyl)-2-hydroxy-propionic acid methyl ester 
• 179128-89-3 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid allyl ester 
• 179128-88-2 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid 2-trimethylsilanyl-ethyl ester 
• 179129-00-1 (E)-3-(4-Allyloxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-bis-allyloxy-phenyl)-ethyl ester 
• 179128-98-4 (E)-3-(3,4-Bis-allyloxy-phenyl)-acrylic acid 2-(3,4-bis-allyloxy-phenyl)-1-methoxycarbonyl-ethyl ester 
• 179128-99-5 (E)-3-(3-Allyloxy-4-methoxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-bis-allyloxy-phenyl)-ethyl ester 
• 179129-04-5 (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 2-(3,4-bis-benzyloxy-phenyl)-1-carboxy-ethyl ester 
• 179128-96-2 (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-bis-benzyloxy-phenyl)-ethyl ester 
• 179128-95-1 (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 2-(3,4-bis-benzyloxy-phenyl)-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl ester 
• 179128-90-6 3-(3,4-Bis-allyloxy-phenyl)-2-hydroxy-propionic acid allyl ester 
• 179129-02-3 (R)-allyl 3-(3,4-bis(allyloxy)phenyl)-2-hydroxypropanoate 
• 179129-03-4 (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-dihydroxy-phenyl)-ethyl ester 

Relevant articles and documents

Salvianolic acids T and U: A pair of atropisomeric trimeric caffeic acids derivatives from root of Salvia miltiorrhiza

Two new trimeric caffeic acids, named salvianolic acids T and U (1 and 2), were isolated from the underground part of Salvia miltiorrhiza. Their structures, consisting of three caffeic acid units, were determined based on extensive 1D- and 2D-spectroscopic analyses and electronic circular dichroism (ECD) calculations.

Hydrolysis of Rosmarinic Acid from Rosemary Extract with Esterases and Lactobacillus johnsonii in Vitro and in a Gastrointestinal Model

Rosmarinic acid (RA) was identified as one of the main components of rosemary extracts and has been ascribed to a number of health benefits. Several studies suggested that after ingestion, RA is metabolized by gut microflora into caffeic acid and derivati

Salvianolic acid L, a potent phenolic antioxidant from Salvia officinalis

Salvianolic acid L, a rosmarinic acid dimer, was isolated from Salvia officinalis and identified as 7,8-dihydroxy-2-(3,4-dihydroxyphenyl)-1,2-dihydronaphthalene-1,3-dicarboxylic acid di(1-carboxy-2-(3,4-dihydroxyphenyl))ethyl ester. Two novel hydrolytic products 7,8-dihydroxy-2-(3,4-dihydroxyphenyl)-1,2-dihydronaphthalene-1,3-dicarboxylic acid and the corresponding 3-monoester were also isolated and characterized. Salvianolic acid L showed strong free radical scavenging activities for DPPH and superoxide anion radicals.

New phenolic glycosides from Anemone chinensis Bunge and their antioxidant activity

ABATRACT: Nine compounds, five phenolic glycosides (1, 2, 4–6), three phenylpropanoids (7–9), and a furanone glycoside (3), were isolated from aqueous soluble extract of the dried roots of Anemone chinensis Bunge. The structures of new compounds (1–4) were elucidated by comprehensive spectroscopic data analysis as well as chemical evidence. Pulsatillanin A (1) demonstrated significant antioxidant effects through scavenging free radical in DPPH assay, and relieved the oxidative stress in LPS-induced RAW 264.7 cells by reducing ROS production, enhancing antioxidant enzyme SOD activity, replenishing depleted GSH in a dose-dependent manner. Western blot analysis revealed that 1 showed antioxidant activity via activating Nrf2 signaling pathway.