23133-34-8Relevant articles and documents
Microwave-mediated Green synthesis of oxadiazole derivatives against inflammatory disease
Sahoo, Biswa Mohan,Panda, Jnyanaranjan,Banik, Bimal Krishna,Sahoo, Binayani
, p. 1307 - 1310 (2020/06/27)
A rapid and efficient microwave-mediated Green synthesis of oxadiazole derivatives (2a-e) is described based on reaction between benzohydrazide and various substituted benzoic acids. The use of microwave irradiation to carry out chemical reactions provide
Electrosynthesis and screening of novel 1,3,4-oxadiazoles as potent and selective antifungal agents
Singh, Sushma,Sharma, Laxmi Kant,Saraswat, Apoorv,Siddiqui, Ibadur R.,Kehri, Harbans K.,Singh, Rana K. Pal
, p. 4237 - 4245 (2013/05/08)
The electrochemical oxidation of aldehyde-N-aroylhydrazone has been studied in the presence of NaClO4 as supporting electrolyte in MeOH solution using cyclic voltammetry and controlled potential electrolysis. The results indicate that intramolecular cyclization of aldehyde-N-aroylhydrazone has been successfully performed at a platinum electrode in an undivided cell with good yields of the corresponding 1,3,4-oxadiazoles at ambient conditions. The reaction products were characterized by spectroscopic methods and a mechanism was deduced from voltammetry studies. The antifungal activity of the synthesized compounds was evaluated on Fusarium oxysporum, Alternaria solani, Candida albicans and Aspergillus niger. The results revealed that all the synthesized compounds have significant antifungal activity against the tested fungi. Among the synthesized derivatives 7b, 7d, 7g, 7h, 7i, 7j and 7r were found to be the most effective antifungal compounds. The Royal Society of Chemistry 2013.
The spectrophotometric study of a fluorescence-enhanced inclusion complex Threaded with β-cyclodextrin: Synthesis and characterization
Chiu, Yi-Hong,Liu, Jui-Hsiang
, p. 3368 - 3374 (2011/04/26)
A novel achiral monomer end-capped with a phenyl-[1,3,4]oxadiazolyl group and threaded through β-cyclodextrin was synthesized to investigate the host-guest interactions in the inclusion complex. 1H NMR studies revealed that one or two eyclodextrin molecules were threaded onto the synthesized achiral monomer, leading to the formation of a fibrous construction of self-assembled inclusion complexes. The formation of a self-assembled inclusion complex was identified using SEM and TEM. The highly ordered alignment of selfassembled supramolecules was confirmed using polarized optical microscopy. We demonstrate an easy process for the fabrication of nano-structured self-assembled inclusion complexes in pyridine/ethanol (1 mL/10 mL) as well as the enhancement of photo-induced fluorescence via monomers end-capped with a phenyl-[1,3,4]oxadiazolyl moiety threaded with β-cyclodextrins.