23947-37-7

Basic information

• Product Name: 4,6-DIMETHYLQUINOLIN-2-OL
• Synonyms: 4,6-DIMETHYLQUINOLIN-2-OL;4,6-DIMETHYL-2-HYDROXYQUINOLINE;2(1H)-Quinolinone, 4,6-dimethyl-;4,6-dimethyl-1H-quinolin-2-one;4,6-dimethylcarbostyril;4,6-dimethylquinolin-2(1H)-one
• CAS NO: 23947-37-7
• Molecular Formula: C₁₁H₁₁NO
• Molecular Weight: 173.22
• Mol File: 23947-37-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 350.9°Cat760mmHg
• Flash Point: 206.5°C
• Appearance: /
• Density: 1.107g/cm³
• Vapor Pressure: 4.26E-05mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: 4,6-DIMETHYLQUINOLIN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DIMETHYLQUINOLIN-2-OL(23947-37-7)
• EPA Substance Registry System: 4,6-DIMETHYLQUINOLIN-2-OL(23947-37-7)

Safety Data

• Hazardous Substances Data: 23947-37-7(Hazardous Substances Data)

Usage

General Description

4,6-DIMETHYLQUINOLIN-2-OL is a chemical compound with the molecular formula C11H11NO. It is a derivative of quinoline and contains a hydroxyl group. The compound is found in some plant species and has been used in research and pharmaceutical applications. It exhibits antioxidant and anti-inflammatory properties, and its structure suggests potential biological activities. Its unique structure and functional groups make it a valuable compound for further study and potential development of new drug compounds.

InChI:InChI=1/C11H11NO/c1-7-3-4-10-9(5-7)8(2)6-11(13)12-10/h3-6H,1-2H3,(H,12,13)

Upstream product

• 2415-85-2 3-oxo-N-(p-tolyl)butanamide 
• 141-97-9 ethyl acetoacetate 
• 106-49-0 p-toluidine 
• 124-38-9 carbon dioxide 
• 107859-39-2 2-(2-Amino-5-methylphenyl)-propen 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 4341-76-8 Ethyl 2-butynoate 
• 103-89-9 4-Methylacetanilide 

Downstream Products

• 3913-18-6 2-chloro-4,6-dimethylquinoline 
• 826-77-7 4,6-dimethylquinoline 
• 53761-42-5 1,4,6-trimethylquinolin-2(1H)-one 
• 123637-75-2 (S)-2-{4-[(2-Acetylamino-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid diethyl ester 
• 123651-23-0 N-[4-[N-(2-amino-4-methylquinolin-6-ylmethyl)-N-(prop-2-ynyl)amino]benzoyl]-L-glutamic acid 
• 123637-09-2 (S)-2-{4-[(2-Chloro-4-methyl-quinolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid 

Relevant articles and documents

Ru-NHC-Catalyzed Asymmetric Hydrogenation of 2-Quinolones to Chiral 3,4-Dihydro-2-Quinolones

Direct enantioselective hydrogenation of unsaturated compounds to generate chiral three-dimensional motifs is one of the most straightforward and important approaches in synthetic chemistry. We realized the Ru(II)-NHC-catalyzed asymmetric hydrogenation of 2-quinolones under mild reaction conditions. Alkyl-, aryl- and halogen-substituted optically active dihydro-2-quinolones were obtained in high yields with moderate to excellent enantioselectivities. The reaction provides an efficient and atom-economic pathway to construct simple chiral 3,4-dihydro-2-quinolones. The desired products could be further reduced to tetrahydroquinolines and octahydroquinolones.

Lactamization of alkenyl C-H bonds to generate 2-quinolinones with triphosgene

A simple and easy-going method is developed to synthesize the analogues of 2-quinolinones by using triphosgene (BTC) as the carbonyl source. In these reactions, both the toxic carbon monoxide (CO) and phosgene are avoided and the 2-quinolinones are obtained in moderate to good yields under mild conditions, all of which are anticipated to be meaningful in both industry and laboratory.

Compounds having anticonvulsion activity, preparing methods thereof and applications of the compounds

The invention provides 7-substituted-5-methyl-1,2,4-triazolo[4,3-a] quinoline and 7-substituted-5-ethoxy-[1,2,4]-triazolo[4,3-a] quinoline compounds having anticonvulsion activity, preparing methods thereof and applications of the compounds in the field of preparing anticonvulsion medicines.