53761-42-5 Usage
General Description
1,4,6-trimethylquinolin-2(1H)-one is a chemical compound with a quinoline ring structure and three methyl groups attached at the 1, 4, and 6 positions. It is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. 1,4,6-trimethylquinolin-2(1H)-one has been found to have potential biological activities, including anti-inflammatory, antioxidant, and anticancer properties. Its molecular structure makes it a versatile starting material for the development of new drugs and compounds with therapeutic potential. Additionally, its unique properties make it a valuable tool for chemical research and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 53761-42-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,7,6 and 1 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 53761-42:
(7*5)+(6*3)+(5*7)+(4*6)+(3*1)+(2*4)+(1*2)=125
125 % 10 = 5
So 53761-42-5 is a valid CAS Registry Number.
53761-42-5Relevant articles and documents
Ru-NHC-Catalyzed Asymmetric Hydrogenation of 2-Quinolones to Chiral 3,4-Dihydro-2-Quinolones
Daniliuc, Constantin,Glorius, Frank,Hu, Tianjiao,Lückemeier, Lukas
, p. 23193 - 23196 (2021/09/25)
Direct enantioselective hydrogenation of unsaturated compounds to generate chiral three-dimensional motifs is one of the most straightforward and important approaches in synthetic chemistry. We realized the Ru(II)-NHC-catalyzed asymmetric hydrogenation of 2-quinolones under mild reaction conditions. Alkyl-, aryl- and halogen-substituted optically active dihydro-2-quinolones were obtained in high yields with moderate to excellent enantioselectivities. The reaction provides an efficient and atom-economic pathway to construct simple chiral 3,4-dihydro-2-quinolones. The desired products could be further reduced to tetrahydroquinolines and octahydroquinolones.
