2397-77-5

Basic information

• Product Name: ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate
• Synonyms: 4H-Pyran-2-carboxylic acid, 4-oxo-6-phenyl-, ethyl ester; Ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate
• CAS NO: 2397-77-5
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.2427
• Mol File: 2397-77-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 431.8°C at 760 mmHg
• Flash Point: 194.7°C
• Density: 1.253g/cm³
• Vapor Pressure: 1.16E-07mmHg at 25°C
• Refractive Index: 1.57
• CAS DataBase Reference: ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate(2397-77-5)
• EPA Substance Registry System: ethyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate(2397-77-5)

Safety Data

• Hazardous Substances Data: 2397-77-5(Hazardous Substances Data)

Upstream product

• 76782-46-2 ethyl 6-phenyl-2,4,6-trioxohexanoate 
• 93-91-4 1-phenylbutan-1,3-dione 
• 1027-41-4 ethyl (E)-2,4-dioxo-6-phenylhex-5-enoate 
• 1027-41-4 2,4-dioxo-6-phenyl-hex-5-enoic acid ethyl ester 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 57409-49-1 methyl 2,4-dioxo-6-phenylhex-5-enoate 
• 64-17-5 ethanol 
• 78526-66-6 methyl 5,6-dibromo-2,4-dioxo-6-phenylhexanoate 
• 1154-90-1 Ethyl 5,6-dibromo-2,4-dioxo-6-phenylhexanoate 

Downstream Products

• 57106-11-3 4-(1,3-dimethyl-2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidene)-6-phenyl-4H-pyran-2-carboxylic acid ethyl ester 
• 57050-20-1 4-oxo-6-phenyl-4H-pyran-2-carboxamide 
• 78296-37-4 4-hydroxy-6-phenylpyridine-2-carboxylic acid 
• 85814-93-3 4-hydroxy-6-phenylpyridine-2-carboxamide 
• 100374-57-0 Methyl 4-oxo-6-phenyl-4H-pyran-2-carboxylate 
• 230617-82-0 4-Hydroxymethyl-6-phenyl-4H-pyran-2-one 
• 2398-05-2 4-Oxo-6-phenyl-4H-pyran-2-carbaldehyde 
• 1241726-41-9 4-oxo-6-phenyl-4H-pyran-2-carbohydrazide 
• 1242141-83-8 N-hydroxy-4-oxo-6-phenyl-4H-pyran-2-carboxamide 
• 1152096-35-9 ethyl 4-hydroxy-6-phenylpyridine-2-carboxylate 
• 1241726-43-1 4-hydroxy-6-phenylpyridine-2-carbohydrazide 
• 1241726-44-2 3-(1,5-diphenyl-1H-pyrazol-3-yl)-2-(2-phenylhydrazono)propionic acid 
• 1241726-45-3 3-(1,5-diphenyl-1H-pyrazol-3-yl)-1H-indole-2-carboxylic acid 
• 1449030-00-5 2-chloro-N-[(cyclohexylcarbamoyl)(4-oxo-6-phenyl-4Hpyran-2-yl)methyl]-N-p-tolylbenzamide 

Relevant articles and documents

Cytotoxic activity assessment, QSAR and docking study of novel bis-carboxamide derivatives of 4-pyrones synthesized by Ugi four-component reaction

Fourteen novel bis-carboxamide derivatives of 4-pyrones were designed and synthesized via Ugi four-component reactions of 4-pyrone carbaldehydes, aromatic amines, isocyanides and carboxylic acids. The cytotoxic activity of synthesized derivatives was eval

Synthesis and reactions of reduced flavones

The cycloadditions of a series of 4H-pyran-4-ones 3c-e with electron-rich dienes 11a,b to give reduced flavones 12 is described. The subsequent reactions of these reduced flavones with HCl, trifluoroacetic anhydride, ethyl anthranilate 19a and anthranilon