24423-87-8

Basic information

• Product Name: 3,4-dihydroisoquinoline 2-oxide
• Synonyms: Isoquinoline, 3,4-dihydro-, 2-oxide
• CAS NO: 24423-87-8
• Molecular Formula: C₉H₉NO
• Molecular Weight: 147.1739
• Mol File: 24423-87-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 311°C at 760 mmHg
• Flash Point: 158.3°C
• Density: 1.14g/cm³
• Vapor Pressure: 0.00106mmHg at 25°C
• Refractive Index: 1.603
• CAS DataBase Reference: 3,4-dihydroisoquinoline 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydroisoquinoline 2-oxide(24423-87-8)
• EPA Substance Registry System: 3,4-dihydroisoquinoline 2-oxide(24423-87-8)

Safety Data

• Hazardous Substances Data: 24423-87-8(Hazardous Substances Data)

Upstream product

• 22901-09-3 2-(2-bromoethyl)benzaldehyde 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 75-05-8 acetonitrile 
• 623-00-7 4-bromobenzenecarbonitrile 

Downstream Products

• 21939-14-0 10-phenyl-(8ar,11ac,11bc)-5,8a,11a,11b-tetrahydro-6H-pyrrolo[3',4':4,5]isoxazolo[3,2-a]isoquinoline-9,11-dione 
• 19332-04-8 2-phenyl-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 72502-79-5 9,9-dimethyl-12,12-diphenyl-5,9,12,13a-tetrahydro-6H-9λ⁵-[1,2]azaphospholo[2',1':2,3][1,3,5,2]oxadiazaphospholo[4,5-a]isoquinoline-10,11-dicarboxylic acid dimethyl ester 
• 19332-08-2 2,2-diphenyl-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 20521-06-6 (8at,12at,12bc)-5,8a,9,10,11,12,12a,12b-octahydro-6H-9r,12c-methano-benzo[4,5]thiazolo[3,2-a]isoquinoline-10ξ,11ξ-dicarboxylic acid dimethyl ester 
• 72502-80-8 9,9,12,12-tetraphenyl-5,9,12,13a-tetrahydro-6H-9λ⁵-[1,2]azaphospholo[2',1':2,3][1,3,5,2]oxadiazaphospholo[4,5-a]isoquinoline-10,11-dicarboxylic acid dimethyl ester 
• 21978-66-5 1-phenyl-1,5,6,10b-tetrahydro-[1,2,4]oxadiazolo[3,2-a]isoquinolin-2-one 
• 89768-84-3 2-phenyl-6,10b-dihydro-5H-isoxazolo[3,2-a]isoquinoline-1-carboxylic acid methyl ester 
• 22278-43-9 2-phenyl-5,6-dihydro-2H-isoxazolo[3,2-a]isoquinoline-1-carboxylic acid ethyl ester 
• 196393-15-4 cis-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinolin-2-yl ethyl ether 
• 196393-15-4 trans-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinolin-2-yl ethyl ether 
• 196393-15-4 (-)-(2S,10bS)-2-ethoxy-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 196393-15-4 (+)-(2R,10bR)-2-ethoxy-1,5,6,10b-tetrahydro-2H-isoxazolo[3,2-a]isoquinoline 
• 3230-65-7 3,4-dihydroisoquinoline 

Relevant articles and documents

Metal-Free Solvent Promoted Oxidation of Benzylic Secondary Amines to Nitrones with H2O2

An environmentally benign protocol for the generation of nitrones from benzylic secondary amines via catalyst-free oxidation of secondary amines using H2O2 in MeOH or CH3CN is described. This methodology provides a selective access to a variety of C-aryl nitrones in yields of 60 to 93%. Several studies have been performed to shed light on the reaction mechanism and the role of the solvent.