245115-25-7 Usage
General Description
"(1S,2R)-Boc-2-amino-1-cyclopentanecarboxylic acid" is a type of organic compound that falls under the category of proteogenic amino acids. As implied by its chemical formula, it features the protective Boc-group (tert-butoxycarbonyl group), a carbamate functionality used to protect amines in peptide synthesis. This particular compound possesses the complex ring structure of cyclopentane in its molecular makeup and includes carboxylic acid and amino functionalities as well. Its (S) and (R) identifiers refer to the absolute stereochemistry of the compound according to Cahn-Ingold-Prelog priority rules. It's used in various laboratory and synthetic applications, specifically in peptide and protein synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 245115-25-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,5,1,1 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 245115-25:
(8*2)+(7*4)+(6*5)+(5*1)+(4*1)+(3*5)+(2*2)+(1*5)=107
107 % 10 = 7
So 245115-25-7 is a valid CAS Registry Number.
245115-25-7Relevant articles and documents
(S,S)-trans-cyclopentane-constrained peptide nucleic acids. A general backbone modification that improves binding affinity and sequence specificity
Pokorski, Jonathan K.,Witschi, Mark A.,Purnell, Bethany L.,Appella, Daniel H.
, p. 15067 - 15073 (2007/10/03)
Replacing the ethylenediamine portion of aminoethylglycine peptide nucleic acids (aegPNAs) with one or more (S,S)-trans-cyclopentane diamine units significantly increases binding affinity and sequence specificity to complementary DNA, making these modifie
Synthesis of enantiomerically pure cis and trans 2-aminocyclopentanecarboxylic acids. Use of proline replacements in potential HIV-protease inhibitors
Noeteberg, Daniel,Branalt, Jonas,Kvarnstroem, Ingemar,Classon, Bjoern,Samuelsson, Bertil,Nillroth, Ulrika,Danielson, U. Helena,Karlen, Anders,Hallberg, Anders
, p. 7975 - 7984 (2007/10/03)
The synthesis of the four diastereomeric 2-aminocyclopentanecarboxylic acids, their use as replacements for proline in potential HIV protease inhibitors containing a hydroxyethylamine dipeptide isostere and the evaluation of the biological activity of these is described.
