249537-15-3

Basic information

• Product Name: 3-Cyclopentene-1-carboxylicacid,2-hydroxy-1-methyl-,methylester(9CI)
• Synonyms: 3-Cyclopentene-1-carboxylicacid,2-hydroxy-1-methyl-,methylester(9CI)
• CAS NO: 249537-15-3
• Molecular Formula: C8H12O3
• Molecular Weight: 156.18
• Product Categories: CARBOXYLICESTER
• Mol File: 249537-15-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 220.2±40.0 °C(Predicted)
• Appearance: /
• Density: 1.156±0.06 g/cm3(Predicted)
• PKA: 13.98±0.40(Predicted)
• CAS DataBase Reference: 3-Cyclopentene-1-carboxylicacid,2-hydroxy-1-methyl-,methylester(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclopentene-1-carboxylicacid,2-hydroxy-1-methyl-,methylester(9CI)(249537-15-3)
• EPA Substance Registry System: 3-Cyclopentene-1-carboxylicacid,2-hydroxy-1-methyl-,methylester(9CI)(249537-15-3)

Safety Data

• Hazardous Substances Data: 249537-15-3(Hazardous Substances Data)

Upstream product

• 206755-00-2 methyl (1S)-1-methyl-2-oxo-3-cyclopentenecarboxylate 
• 108-05-4 vinyl acetate 
• 249536-82-1 methyl (1S,2S)-2-acetoxy-1-methyl-3-cyclopentenecarboxylate 
• 139616-47-0 methyl (1S)-2-((1R,2R)-2-hydroxycycloheptan-1-yl)oxy-1-methyl-2-cyclopenten-1-carboxylate 
• 206760-79-4 methyl (1S)-2,2-[(1'R,2'R)-cycloheptane-1',2'-dioxy]-1-methyl-3-cyclopentenecarboxylate 
• 206760-78-3 methyl (1S,3S)-2,2-[(1'R,2'R)-cycloheptane-1',2'-dioxy]-3-iodo-1-methylcyclopentane-carboxylate 
• 163131-87-1 1-methyl-2-oxo-cyclopent-3-enecarboxylic acid methyl ester 
• 30680-84-3 methyl 1-methyl-2-oxocyclopentane-1-carboxylate 
• 10472-24-9 methyl 2-oxocyclopentane-1-carboxylate 

Downstream Products

• 206755-01-3 methyl (1S,2S)-2-hydroxy-1-methyl-3-cyclopentenecarboxylate 
• 249536-82-1 methyl (1S,2S)-2-acetoxy-1-methyl-3-cyclopentenecarboxylate 
• 249537-10-8 (1S,4S)-4-Hydroxy-1-methyl-cyclopent-2-enecarboxylic acid methyl ester 
• 249537-10-8 methyl (1R,4R)-4-hydroxy-1-methyl-2-cyclopentenecarboxylate 
• 206755-02-4 methyl (1S,4S)-4-hydroxy-1-methyl-2-cyclopentenecarboxylate 

Relevant articles and documents

A short formal total synthesis of (±)-hirsutic acid

A short formal total synthesis of (±)-hirsutic acid is described using a Claisen rearrangement and a radical cascade as the key steps. The radical sequence involves an intermolecular addition of a radical derived from a xanthate followed by a cyclization and transfer of the xanthate group.

Enantio- and diastereoselective synthesis of 4'-α-substituted carbocyclic nucleosides

Enantio- and diastereoselective synthesis of 4-α-alkylcarbovir derivatives 5 were achieved based on Sakai's asymmetric alkylation of β- keto esters. The key carbocyclic intermediate 14 was synthesized from 8 via an eleven-step sequence. Coupling of 14 with 2-amino-6-chloropurine followed by desilylation and subsequent hydrolysis gave the target compounds 5 in moderate yields.